Recombinant multi-species HADHA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HADHA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes the alpha subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the alpha subunit catalyzing the 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase activities. Mutations in this gene result in trifunctional protein deficiency or LCHAD deficiency. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 78 kDa gastrin-binding protein,ECHA,GBP,HADH,HADHA,Hadha,LCEH,LCHAD,MTPA,Monolysocardiolipin acyltransferase,Mtpa,RGD1560655,TP-ALPHA,TP-alpha,Trifunctional enzyme subunit alpha,mitochondrial

Target products collectionGo to HADHA products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP7902-Ag-1/ GM-Tg-hg-IP7902-Ag-2 Human HADHA protein Human
GM-Tg-rg-IP7902-Ag-1/ GM-Tg-rg-IP7902-Ag-2 Rat HADHA protein Rat
GM-Tg-mg-IP7902-Ag-1/ GM-Tg-mg-IP7902-Ag-2 Mouse HADHA protein Mouse
GM-Tg-cynog-IP7902-Ag-1/ GM-Tg-cynog-IP7902-Ag-2 Cynomolgus/Rhesus macaque HADHA protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP7902-Ag-1/ GM-Tg-felg-IP7902-Ag-2 Feline HADHA protein Feline
GM-Tg-cang-IP7902-Ag-1/ GM-Tg-cang-IP7902-Ag-2 Canine HADHA protein Canine
GM-Tg-bovg-IP7902-Ag-1/ GM-Tg-bovg-IP7902-Ag-2 Bovine HADHA protein Bovine
GM-Tg-equg-IP7902-Ag-1/ GM-Tg-equg-IP7902-Ag-2 Equine HADHA protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP7902-Ag-1/ GM-Tg-hg-IP7902-Ag-2; GM-Tg-rg-IP7902-Ag-1/ GM-Tg-rg-IP7902-Ag-2;
GM-Tg-mg-IP7902-Ag-1/ GM-Tg-mg-IP7902-Ag-2; GM-Tg-cynog-IP7902-Ag-1/ GM-Tg-cynog-IP7902-Ag-2;
GM-Tg-felg-IP7902-Ag-1/ GM-Tg-felg-IP7902-Ag-2; GM-Tg-cang-IP7902-Ag-1/ GM-Tg-cang-IP7902-Ag-2;
GM-Tg-bovg-IP7902-Ag-1/ GM-Tg-bovg-IP7902-Ag-2; GM-Tg-equg-IP7902-Ag-1/ GM-Tg-equg-IP7902-Ag-2
Products Name HADHA protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name HADHA
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HADHA protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.