Recombinant multi-species CNOT7 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CNOT7 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X. [provided by RefSeq, Apr 2016]
The Alternative Names of target: BTG1-binding factor 1,CAF-1,CAF1,CCR4-NOT transcription complex subunit 7,CCR4-associated factor 1 (CAF-1),CNOT7,Caf1,Caf1a,Cnot7,Pop2,hCAF-1

Target products collectionGo to CNOT7 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP7842-Ag-1/ GM-Tg-hg-IP7842-Ag-2 Human CNOT7 protein Human
GM-Tg-rg-IP7842-Ag-1/ GM-Tg-rg-IP7842-Ag-2 Rat CNOT7 protein Rat
GM-Tg-mg-IP7842-Ag-1/ GM-Tg-mg-IP7842-Ag-2 Mouse CNOT7 protein Mouse
GM-Tg-cynog-IP7842-Ag-1/ GM-Tg-cynog-IP7842-Ag-2 Cynomolgus/Rhesus macaque CNOT7 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP7842-Ag-1/ GM-Tg-felg-IP7842-Ag-2 Feline CNOT7 protein Feline
GM-Tg-cang-IP7842-Ag-1/ GM-Tg-cang-IP7842-Ag-2 Canine CNOT7 protein Canine
GM-Tg-bovg-IP7842-Ag-1/ GM-Tg-bovg-IP7842-Ag-2 Bovine CNOT7 protein Bovine
GM-Tg-equg-IP7842-Ag-1/ GM-Tg-equg-IP7842-Ag-2 Equine CNOT7 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP7842-Ag-1/ GM-Tg-hg-IP7842-Ag-2; GM-Tg-rg-IP7842-Ag-1/ GM-Tg-rg-IP7842-Ag-2;
GM-Tg-mg-IP7842-Ag-1/ GM-Tg-mg-IP7842-Ag-2; GM-Tg-cynog-IP7842-Ag-1/ GM-Tg-cynog-IP7842-Ag-2;
GM-Tg-felg-IP7842-Ag-1/ GM-Tg-felg-IP7842-Ag-2; GM-Tg-cang-IP7842-Ag-1/ GM-Tg-cang-IP7842-Ag-2;
GM-Tg-bovg-IP7842-Ag-1/ GM-Tg-bovg-IP7842-Ag-2; GM-Tg-equg-IP7842-Ag-1/ GM-Tg-equg-IP7842-Ag-2
Products Name CNOT7 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name CNOT7
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CNOT7 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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