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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X. [provided by RefSeq, Apr 2016]
| Target ID |
GM-IP7842
|
| Target Name |
CNOT7
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
29883
|
| Gene ID |
100050103 (Equus caballus), 101080782 (Felis catus), 18983 (Mus musculus), 29883 (Homo sapiens) 306492 (Rattus norvegicus), 482895 (Canis lupus familiaris), 508055 (Bos taurus), 702192 (Macaca mulatta)
|
| Target Alternative Names |
BTG1-binding factor 1,CAF-1,CAF1,CCR4-NOT transcription complex subunit 7,CCR4-associated factor 1 (CAF-1),CNOT7,Caf1,Caf1a,Cnot7,Pop2,hCAF-1
|
| Uniprot Accession |
Q60809,Q9UIV1,Q3ZC01
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000005798, ENSMUSG00000031601, ENSG00000198791, ENSCAFG00845014580, ENSBTAG00000018036, ENSMMUG00000001873
|
Pre-made viral vector of CNOT7 cDNA Clones/ORF Plasmid
CNOT7 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo29883 | Pre-made Human CNOT7/CAF1/CAF-1 siRNA oligo Duplex | 29883 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo306492 | Pre-made Rat Cnot7 siRNA oligo Duplex | 306492 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo18983 | Pre-made Mouse Cnot7/Caf1/Pop2 siRNA oligo Duplex | 18983 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo702192 | Pre-made Cynomolgus/Rhesus macaque CNOT7 siRNA oligo Duplex | 702192 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101080782 | Pre-made Cat/Feline CNOT7 siRNA oligo Duplex | 101080782 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo482895 | Pre-made Dog/Canine CNOT7 siRNA oligo Duplex | 482895 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo508055 | Pre-made Bovines/Cattle CNOT7 siRNA oligo Duplex | 508055 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100050103 | Pre-made Equine/Horse CNOT7 siRNA oligo Duplex | 100050103 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CNOT7 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP7842-Ab | Human | Anti-Human CNOT7 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP7842-Ab | Rat | Anti-Rat CNOT7 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP7842-Ab | Mouse | Anti-Mouse CNOT7 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP7842-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CNOT7 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP7842-Ab | Cat/Feline | Anti-Cat/Feline CNOT7 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP7842-Ab | Dog/Canine | Anti-Dog/Canine CNOT7 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP7842-Ab | Bovines/Cattle | Anti-Bovines/Cattle CNOT7 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP7842-Ab | Equine/Horse | Anti-Equine/Horse CNOT7 monoclonal antibody | mab | | Detail |
CNOT7 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP7842-Ag | Human | Human CNOT7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP7842-Ag | Rat | Rat CNOT7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP7842-Ag | Mouse | Mouse CNOT7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP7842-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CNOT7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP7842-Ag | Cat/Feline | Cat/Feline CNOT7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP7842-Ag | Dog/Canine | Dog/Canine CNOT7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP7842-Ag | Bovines/Cattle | Bovines/Cattle CNOT7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP7842-Ag | Equine/Horse | Equine/Horse CNOT7 recombinant protein | Mammalian cell | Detail |