Recombinant multi-species MSH6 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MSH6 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described. [provided by RefSeq, Jul 2013]
The Alternative Names of target: DNA mismatch repair protein Msh6,G/T mismatch-binding protein (GTBP,GTBP,GTMBP,GTMBP),Gtmbp,HNPCC5,HSAP,LYNCH5,MMRCS3,MSH-6,MSH6,Msh6,MutS protein homolog 6,MutS-alpha 160 kDa subunit (p160),hMSH6,p160

Target products collectionGo to MSH6 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP7809-Ag-1/ GM-Tg-hg-IP7809-Ag-2 Human MSH6 protein Human
GM-Tg-rg-IP7809-Ag-1/ GM-Tg-rg-IP7809-Ag-2 Rat MSH6 protein Rat
GM-Tg-mg-IP7809-Ag-1/ GM-Tg-mg-IP7809-Ag-2 Mouse MSH6 protein Mouse
GM-Tg-cynog-IP7809-Ag-1/ GM-Tg-cynog-IP7809-Ag-2 Cynomolgus/Rhesus macaque MSH6 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP7809-Ag-1/ GM-Tg-felg-IP7809-Ag-2 Feline MSH6 protein Feline
GM-Tg-cang-IP7809-Ag-1/ GM-Tg-cang-IP7809-Ag-2 Canine MSH6 protein Canine
GM-Tg-bovg-IP7809-Ag-1/ GM-Tg-bovg-IP7809-Ag-2 Bovine MSH6 protein Bovine
GM-Tg-equg-IP7809-Ag-1/ GM-Tg-equg-IP7809-Ag-2 Equine MSH6 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP7809-Ag-1/ GM-Tg-hg-IP7809-Ag-2; GM-Tg-rg-IP7809-Ag-1/ GM-Tg-rg-IP7809-Ag-2;
GM-Tg-mg-IP7809-Ag-1/ GM-Tg-mg-IP7809-Ag-2; GM-Tg-cynog-IP7809-Ag-1/ GM-Tg-cynog-IP7809-Ag-2;
GM-Tg-felg-IP7809-Ag-1/ GM-Tg-felg-IP7809-Ag-2; GM-Tg-cang-IP7809-Ag-1/ GM-Tg-cang-IP7809-Ag-2;
GM-Tg-bovg-IP7809-Ag-1/ GM-Tg-bovg-IP7809-Ag-2; GM-Tg-equg-IP7809-Ag-1/ GM-Tg-equg-IP7809-Ag-2
Products Name MSH6 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name MSH6
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MSH6 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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