Recombinant multi-species GRB10 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GRB10 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner, with expression observed from the paternal allele in the brain, and from the maternal allele in the placental trophoblasts. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2010]
The Alternative Names of target: 5730571D09Rik,GRB-IR,GRB10,GRB10 adapter protein,Grb-10,Grb10,Growth factor receptor-bound protein 10,IRBP,Insulin receptor-binding protein Grb-IR,MEG1,Meg1,RGD1566234,RSS,mKIAA0207

Target products collectionGo to GRB10 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP7737-Ag-1/ GM-Tg-hg-IP7737-Ag-2 Human GRB10 protein Human
GM-Tg-rg-IP7737-Ag-1/ GM-Tg-rg-IP7737-Ag-2 Rat GRB10 protein Rat
GM-Tg-mg-IP7737-Ag-1/ GM-Tg-mg-IP7737-Ag-2 Mouse GRB10 protein Mouse
GM-Tg-cynog-IP7737-Ag-1/ GM-Tg-cynog-IP7737-Ag-2 Cynomolgus/Rhesus macaque GRB10 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP7737-Ag-1/ GM-Tg-felg-IP7737-Ag-2 Feline GRB10 protein Feline
GM-Tg-cang-IP7737-Ag-1/ GM-Tg-cang-IP7737-Ag-2 Canine GRB10 protein Canine
GM-Tg-bovg-IP7737-Ag-1/ GM-Tg-bovg-IP7737-Ag-2 Bovine GRB10 protein Bovine
GM-Tg-equg-IP7737-Ag-1/ GM-Tg-equg-IP7737-Ag-2 Equine GRB10 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP7737-Ag-1/ GM-Tg-hg-IP7737-Ag-2; GM-Tg-rg-IP7737-Ag-1/ GM-Tg-rg-IP7737-Ag-2;
GM-Tg-mg-IP7737-Ag-1/ GM-Tg-mg-IP7737-Ag-2; GM-Tg-cynog-IP7737-Ag-1/ GM-Tg-cynog-IP7737-Ag-2;
GM-Tg-felg-IP7737-Ag-1/ GM-Tg-felg-IP7737-Ag-2; GM-Tg-cang-IP7737-Ag-1/ GM-Tg-cang-IP7737-Ag-2;
GM-Tg-bovg-IP7737-Ag-1/ GM-Tg-bovg-IP7737-Ag-2; GM-Tg-equg-IP7737-Ag-1/ GM-Tg-equg-IP7737-Ag-2
Products Name GRB10 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name GRB10
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GRB10 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.