Explore GRB10 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner, with expression observed from the paternal allele in the brain, and from the maternal allele in the placental trophoblasts. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2010]
| Target ID |
GM-IP7737
|
| Target Name |
GRB10
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
2887
|
| Gene ID |
100052610 (Equus caballus), 101083918 (Felis catus), 14783 (Mus musculus), 2887 (Homo sapiens) 407210 (Bos taurus), 498416 (Rattus norvegicus), 607755 (Canis lupus familiaris), 694786 (Macaca mulatta)
|
| Target Alternative Names |
5730571D09Rik,GRB-IR,GRB10,GRB10 adapter protein,Grb-10,Grb10,Growth factor receptor-bound protein 10,IRBP,Insulin receptor-binding protein Grb-IR,MEG1,Meg1,RGD1566234,RSS,mKIAA0207
|
| Uniprot Accession |
Q60760,Q13322,P0CE43
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000024158, ENSMUSG00000020176, ENSG00000106070, ENSBTAG00000017086, ENSCAFG00845010745, ENSMMUG00000019992
|
Pre-made viral vector of GRB10 cDNA Clones/ORF Plasmid
GRB10 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2887 | Pre-made Human GRB10/RSS/IRBP siRNA oligo Duplex | 2887 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo498416 | Pre-made Rat Grb10/RGD1566234 siRNA oligo Duplex | 498416 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14783 | Pre-made Mouse Grb10/Meg1/mKIAA0207 siRNA oligo Duplex | 14783 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo694786 | Pre-made Cynomolgus/Rhesus macaque GRB10 siRNA oligo Duplex | 694786 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101083918 | Pre-made Cat/Feline GRB10 siRNA oligo Duplex | 101083918 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo607755 | Pre-made Dog/Canine GRB10 siRNA oligo Duplex | 607755 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo407210 | Pre-made Bovines/Cattle GRB10 siRNA oligo Duplex | 407210 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100052610 | Pre-made Equine/Horse GRB10 siRNA oligo Duplex | 100052610 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
GRB10 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP7737-Ab | Human | Anti-Human GRB10 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP7737-Ab | Rat | Anti-Rat GRB10 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP7737-Ab | Mouse | Anti-Mouse GRB10 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP7737-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque GRB10 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP7737-Ab | Cat/Feline | Anti-Cat/Feline GRB10 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP7737-Ab | Dog/Canine | Anti-Dog/Canine GRB10 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP7737-Ab | Bovines/Cattle | Anti-Bovines/Cattle GRB10 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP7737-Ab | Equine/Horse | Anti-Equine/Horse GRB10 monoclonal antibody | mab | | Detail |
GRB10 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP7737-Ag | Human | Human GRB10 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP7737-Ag | Rat | Rat GRB10 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP7737-Ag | Mouse | Mouse GRB10 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP7737-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque GRB10 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP7737-Ag | Cat/Feline | Cat/Feline GRB10 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP7737-Ag | Dog/Canine | Dog/Canine GRB10 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP7737-Ag | Bovines/Cattle | Bovines/Cattle GRB10 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP7737-Ag | Equine/Horse | Equine/Horse GRB10 recombinant protein | Mammalian cell | Detail |