Recombinant multi-species GRB2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GRB2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
The Alternative Names of target: ASH,Adapter protein GRB2,Ash,Ash-psi,EGFRBP-GRB2,GRB2,Grb2,Grb3-3,Growth factor receptor-bound protein 2,MST084,MSTP084,NCKAP2,Protein Ash,SH2/SH3 adapter GRB2

Target products collectionGo to GRB2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP7736-Ag-1/ GM-Tg-hg-IP7736-Ag-2 Human GRB2 protein Human
GM-Tg-rg-IP7736-Ag-1/ GM-Tg-rg-IP7736-Ag-2 Rat GRB2 protein Rat
GM-Tg-mg-IP7736-Ag-1/ GM-Tg-mg-IP7736-Ag-2 Mouse GRB2 protein Mouse
GM-Tg-cynog-IP7736-Ag-1/ GM-Tg-cynog-IP7736-Ag-2 Cynomolgus/Rhesus macaque GRB2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP7736-Ag-1/ GM-Tg-felg-IP7736-Ag-2 Feline GRB2 protein Feline
GM-Tg-cang-IP7736-Ag-1/ GM-Tg-cang-IP7736-Ag-2 Canine GRB2 protein Canine
GM-Tg-bovg-IP7736-Ag-1/ GM-Tg-bovg-IP7736-Ag-2 Bovine GRB2 protein Bovine
GM-Tg-equg-IP7736-Ag-1/ GM-Tg-equg-IP7736-Ag-2 Equine GRB2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP7736-Ag-1/ GM-Tg-hg-IP7736-Ag-2; GM-Tg-rg-IP7736-Ag-1/ GM-Tg-rg-IP7736-Ag-2;
GM-Tg-mg-IP7736-Ag-1/ GM-Tg-mg-IP7736-Ag-2; GM-Tg-cynog-IP7736-Ag-1/ GM-Tg-cynog-IP7736-Ag-2;
GM-Tg-felg-IP7736-Ag-1/ GM-Tg-felg-IP7736-Ag-2; GM-Tg-cang-IP7736-Ag-1/ GM-Tg-cang-IP7736-Ag-2;
GM-Tg-bovg-IP7736-Ag-1/ GM-Tg-bovg-IP7736-Ag-2; GM-Tg-equg-IP7736-Ag-1/ GM-Tg-equg-IP7736-Ag-2
Products Name GRB2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name GRB2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GRB2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.