Explore GRB2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
| Target ID |
GM-IP7736
|
| Target Name |
GRB2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2885
|
| Gene ID |
100051866 (Equus caballus), 101099916 (Felis catus), 14784 (Mus musculus), 2885 (Homo sapiens)
483312 (Canis lupus familiaris), 535298 (Bos taurus), 702041 (Macaca mulatta), 81504 (Rattus norvegicus)
|
| Target Alternative Names |
ASH,Adapter protein GRB2,Ash,Ash-psi,EGFRBP-GRB2,GRB2,Grb2,Grb3-3,Growth factor receptor-bound protein 2,MST084,MSTP084,NCKAP2,Protein Ash,SH2/SH3 adapter GRB2
|
| Uniprot Accession |
Q60631,P62993,P62994
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000010007, ENSMUSG00000059923, ENSG00000177885, ENSCAFG00845026938, ENSBTAG00000004736, ENSMMUG00000004756
|
Pre-made viral vector of GRB2 cDNA Clones/ORF Plasmid
GRB2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2885 | Pre-made Human GRB2/ASH/Grb3-3 siRNA oligo Duplex | 2885 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo81504 | Pre-made Rat Grb2/Ash-psi siRNA oligo Duplex | 81504 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14784 | Pre-made Mouse Grb2/Ash siRNA oligo Duplex | 14784 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo702041 | Pre-made Cynomolgus/Rhesus macaque GRB2 siRNA oligo Duplex | 702041 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101099916 | Pre-made Cat/Feline GRB2 siRNA oligo Duplex | 101099916 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo483312 | Pre-made Dog/Canine GRB2 siRNA oligo Duplex | 483312 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo535298 | Pre-made Bovines/Cattle GRB2 siRNA oligo Duplex | 535298 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100051866 | Pre-made Equine/Horse GRB2 siRNA oligo Duplex | 100051866 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
GRB2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP7736-Ab | Human | Anti-Human GRB2 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP7736-Ab | Rat | Anti-Rat GRB2 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP7736-Ab | Mouse | Anti-Mouse GRB2 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP7736-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque GRB2 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP7736-Ab | Cat/Feline | Anti-Cat/Feline GRB2 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP7736-Ab | Dog/Canine | Anti-Dog/Canine GRB2 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP7736-Ab | Bovines/Cattle | Anti-Bovines/Cattle GRB2 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP7736-Ab | Equine/Horse | Anti-Equine/Horse GRB2 monoclonal antibody | mab | | Detail |
GRB2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP7736-Ag | Human | Human GRB2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP7736-Ag | Rat | Rat GRB2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP7736-Ag | Mouse | Mouse GRB2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP7736-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque GRB2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP7736-Ag | Cat/Feline | Cat/Feline GRB2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP7736-Ag | Dog/Canine | Dog/Canine GRB2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP7736-Ag | Bovines/Cattle | Bovines/Cattle GRB2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP7736-Ag | Equine/Horse | Equine/Horse GRB2 recombinant protein | Mammalian cell | Detail |
