Recombinant multi-species PNPLA1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PNPLA1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene belongs to the patatin-like phospholipase (PNPLA) family, which is characterized by the presence of a highly conserved patatin domain. PNPLA family members have diverse lipolytic and acyltransferase activities, and are key elements in lipid metabolism. While other members of this family have been well characterized, the function of this gene remained an enigma. However, recent studies show that this gene is expressed in the skin epidermal keratinocytes, and has a role in glycerophospholipid metabolism in the cutaneous barrier. Consistent with these observations, mutations in this gene are associated with ichthyosis in human (autosomal recessive congenital ichthyoses, ARCI) and dog. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2012]
The Alternative Names of target: ARCI10,Omega-hydroxyceramide transacylase,PNPLA1,Patatin-like phospholipase domain-containing protein 1,Pnpla1,dJ50J22.1

Target products collectionGo to PNPLA1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP7700-Ag-1/ GM-Tg-hg-IP7700-Ag-2 Human PNPLA1 protein Human
GM-Tg-rg-IP7700-Ag-1/ GM-Tg-rg-IP7700-Ag-2 Rat PNPLA1 protein Rat
GM-Tg-mg-IP7700-Ag-1/ GM-Tg-mg-IP7700-Ag-2 Mouse PNPLA1 protein Mouse
GM-Tg-cynog-IP7700-Ag-1/ GM-Tg-cynog-IP7700-Ag-2 Cynomolgus/Rhesus macaque PNPLA1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP7700-Ag-1/ GM-Tg-felg-IP7700-Ag-2 Feline PNPLA1 protein Feline
GM-Tg-cang-IP7700-Ag-1/ GM-Tg-cang-IP7700-Ag-2 Canine PNPLA1 protein Canine
GM-Tg-bovg-IP7700-Ag-1/ GM-Tg-bovg-IP7700-Ag-2 Bovine PNPLA1 protein Bovine
GM-Tg-equg-IP7700-Ag-1/ GM-Tg-equg-IP7700-Ag-2 Equine PNPLA1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP7700-Ag-1/ GM-Tg-hg-IP7700-Ag-2; GM-Tg-rg-IP7700-Ag-1/ GM-Tg-rg-IP7700-Ag-2;
GM-Tg-mg-IP7700-Ag-1/ GM-Tg-mg-IP7700-Ag-2; GM-Tg-cynog-IP7700-Ag-1/ GM-Tg-cynog-IP7700-Ag-2;
GM-Tg-felg-IP7700-Ag-1/ GM-Tg-felg-IP7700-Ag-2; GM-Tg-cang-IP7700-Ag-1/ GM-Tg-cang-IP7700-Ag-2;
GM-Tg-bovg-IP7700-Ag-1/ GM-Tg-bovg-IP7700-Ag-2; GM-Tg-equg-IP7700-Ag-1/ GM-Tg-equg-IP7700-Ag-2
Products Name PNPLA1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PNPLA1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PNPLA1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.