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Target
sublocation: Introcelluar Protein.
The protein encoded by this gene belongs to the patatin-like phospholipase (PNPLA) family, which is characterized by the presence of a highly conserved patatin domain. PNPLA family members have diverse lipolytic and acyltransferase activities, and are key elements in lipid metabolism. While other members of this family have been well characterized, the function of this gene remained an enigma. However, recent studies show that this gene is expressed in the skin epidermal keratinocytes, and has a role in glycerophospholipid metabolism in the cutaneous barrier. Consistent with these observations, mutations in this gene are associated with ichthyosis in human (autosomal recessive congenital ichthyoses, ARCI) and dog. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2012]
| Target ID |
GM-IP7700
|
| Target Name |
PNPLA1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
285848
|
| Gene ID |
100063661 (Equus caballus), 100426523 (Macaca mulatta), 101091788 (Felis catus), 285848 (Homo sapiens) 361812 (Rattus norvegicus), 433091 (Mus musculus), 481763 (Canis lupus familiaris), 786888 (Bos taurus)
|
| Target Alternative Names |
ARCI10,Omega-hydroxyceramide transacylase,PNPLA1,Patatin-like phospholipase domain-containing protein 1,Pnpla1,dJ50J22.1
|
| Uniprot Accession |
Q8N8W4,Q3V1D5
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000012343, ENSMMUG00000000685, ENSG00000180316, ENSMUSG00000043286, ENSCAFG00845008874, ENSBTAG00000015118
|
PNPLA1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo285848 | Pre-made Human PNPLA1/ARCI10/dJ50J22.1 siRNA oligo Duplex | 285848 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo361812 | Pre-made Rat Pnpla1 siRNA oligo Duplex | 361812 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo433091 | Pre-made Mouse Pnpla1 siRNA oligo Duplex | 433091 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100426523 | Pre-made Cynomolgus/Rhesus macaque PNPLA1 siRNA oligo Duplex | 100426523 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101091788 | Pre-made Cat/Feline PNPLA1 siRNA oligo Duplex | 101091788 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo481763 | Pre-made Dog/Canine PNPLA1 siRNA oligo Duplex | 481763 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo786888 | Pre-made Bovines/Cattle PNPLA1 siRNA oligo Duplex | 786888 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100063661 | Pre-made Equine/Horse PNPLA1 siRNA oligo Duplex | 100063661 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PNPLA1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP7700-Ab | Human | Anti-Human PNPLA1 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP7700-Ab | Rat | Anti-Rat PNPLA1 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP7700-Ab | Mouse | Anti-Mouse PNPLA1 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP7700-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PNPLA1 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP7700-Ab | Cat/Feline | Anti-Cat/Feline PNPLA1 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP7700-Ab | Dog/Canine | Anti-Dog/Canine PNPLA1 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP7700-Ab | Bovines/Cattle | Anti-Bovines/Cattle PNPLA1 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP7700-Ab | Equine/Horse | Anti-Equine/Horse PNPLA1 monoclonal antibody | mab | | Detail |
PNPLA1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP7700-Ag | Human | Human PNPLA1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP7700-Ag | Rat | Rat PNPLA1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP7700-Ag | Mouse | Mouse PNPLA1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP7700-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PNPLA1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP7700-Ag | Cat/Feline | Cat/Feline PNPLA1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP7700-Ag | Dog/Canine | Dog/Canine PNPLA1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP7700-Ag | Bovines/Cattle | Bovines/Cattle PNPLA1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP7700-Ag | Equine/Horse | Equine/Horse PNPLA1 recombinant protein | Mammalian cell | Detail |