Recombinant multi-species MMADHC protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MMADHC protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a mitochondrial protein that is involved in an early step of vitamin B12 metabolism. Vitamin B12 (cobalamin) is essential for normal development and survival in humans. Mutations in this gene cause methylmalonic aciduria and homocystinuria type cblD (MMADHC), a disorder of cobalamin metabolism that is characterized by decreased levels of the coenzymes adenosylcobalamin and methylcobalamin. Pseudogenes have been identified on chromosomes 11 and X.[provided by RefSeq, Nov 2008]
The Alternative Names of target: 2010311D03Rik,C2H2ORF25,C2orf25,CL25022,CblD,Cobalamin trafficking protein CblD,HMAD,MACD,MAHCD,MMADHC,Methylmalonic aciduria and homocystinuria type D protein,Mmadhc,RGD1303272,cblD,mitochondrial

Target products collectionGo to MMADHC products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP7470-Ag-1/ GM-Tg-hg-IP7470-Ag-2 Human MMADHC protein Human
GM-Tg-rg-IP7470-Ag-1/ GM-Tg-rg-IP7470-Ag-2 Rat MMADHC protein Rat
GM-Tg-mg-IP7470-Ag-1/ GM-Tg-mg-IP7470-Ag-2 Mouse MMADHC protein Mouse
GM-Tg-cynog-IP7470-Ag-1/ GM-Tg-cynog-IP7470-Ag-2 Cynomolgus/Rhesus macaque MMADHC protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP7470-Ag-1/ GM-Tg-felg-IP7470-Ag-2 Feline MMADHC protein Feline
GM-Tg-cang-IP7470-Ag-1/ GM-Tg-cang-IP7470-Ag-2 Canine MMADHC protein Canine
GM-Tg-bovg-IP7470-Ag-1/ GM-Tg-bovg-IP7470-Ag-2 Bovine MMADHC protein Bovine
GM-Tg-equg-IP7470-Ag-1/ GM-Tg-equg-IP7470-Ag-2 Equine MMADHC protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP7470-Ag-1/ GM-Tg-hg-IP7470-Ag-2; GM-Tg-rg-IP7470-Ag-1/ GM-Tg-rg-IP7470-Ag-2;
GM-Tg-mg-IP7470-Ag-1/ GM-Tg-mg-IP7470-Ag-2; GM-Tg-cynog-IP7470-Ag-1/ GM-Tg-cynog-IP7470-Ag-2;
GM-Tg-felg-IP7470-Ag-1/ GM-Tg-felg-IP7470-Ag-2; GM-Tg-cang-IP7470-Ag-1/ GM-Tg-cang-IP7470-Ag-2;
GM-Tg-bovg-IP7470-Ag-1/ GM-Tg-bovg-IP7470-Ag-2; GM-Tg-equg-IP7470-Ag-1/ GM-Tg-equg-IP7470-Ag-2
Products Name MMADHC protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name MMADHC
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MMADHC protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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