Explore MMADHC gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
This gene encodes a mitochondrial protein that is involved in an early step of vitamin B12 metabolism. Vitamin B12 (cobalamin) is essential for normal development and survival in humans. Mutations in this gene cause methylmalonic aciduria and homocystinuria type cblD (MMADHC), a disorder of cobalamin metabolism that is characterized by decreased levels of the coenzymes adenosylcobalamin and methylcobalamin. Pseudogenes have been identified on chromosomes 11 and X.[provided by RefSeq, Nov 2008]
| Target ID |
GM-IP7470
|
| Target Name |
MMADHC
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
27249
|
| Gene ID |
100050023 (Equus caballus), 101099647 (Felis catus), 109129 (Mus musculus), 27249 (Homo sapiens)
362134 (Rattus norvegicus), 476145 (Canis lupus familiaris), 521533 (Bos taurus), 693783 (Macaca mulatta)
|
| Target Alternative Names |
2010311D03Rik,C2H2ORF25,C2orf25,CL25022,CblD,Cobalamin trafficking protein CblD,HMAD,MACD,MAHCD,MMADHC,Methylmalonic aciduria and homocystinuria type D protein,Mmadhc,RGD1303272,cblD,mitochondrial
|
| Uniprot Accession |
Q99LS1,Q9H3L0,Q6AYQ6
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000014503, ENSMUSG00000026766, ENSG00000168288, ENSCAFG00845007815, ENSBTAG00000015962, ENSMMUG00000005633
|
MMADHC siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo27249 | Pre-made Human MMADHC/HMAD/MACD siRNA oligo Duplex | 27249 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo362134 | Pre-made Rat Mmadhc/CblD/RGD1303272 siRNA oligo Duplex | 362134 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo109129 | Pre-made Mouse Mmadhc/CblD/2010311D03Rik siRNA oligo Duplex | 109129 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo693783 | Pre-made Cynomolgus/Rhesus macaque MMADHC siRNA oligo Duplex | 693783 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101099647 | Pre-made Cat/Feline MMADHC siRNA oligo Duplex | 101099647 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo476145 | Pre-made Dog/Canine MMADHC siRNA oligo Duplex | 476145 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo521533 | Pre-made Bovines/Cattle MMADHC/C2H2ORF25 siRNA oligo Duplex | 521533 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100050023 | Pre-made Equine/Horse MMADHC siRNA oligo Duplex | 100050023 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
MMADHC antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP7470-Ab | Human | Anti-Human MMADHC monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP7470-Ab | Rat | Anti-Rat MMADHC monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP7470-Ab | Mouse | Anti-Mouse MMADHC monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP7470-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque MMADHC monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP7470-Ab | Cat/Feline | Anti-Cat/Feline MMADHC monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP7470-Ab | Dog/Canine | Anti-Dog/Canine MMADHC monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP7470-Ab | Bovines/Cattle | Anti-Bovines/Cattle MMADHC monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP7470-Ab | Equine/Horse | Anti-Equine/Horse MMADHC monoclonal antibody | mab | | Detail |
MMADHC recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP7470-Ag | Human | Human MMADHC recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP7470-Ag | Rat | Rat MMADHC recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP7470-Ag | Mouse | Mouse MMADHC recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP7470-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque MMADHC recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP7470-Ag | Cat/Feline | Cat/Feline MMADHC recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP7470-Ag | Dog/Canine | Dog/Canine MMADHC recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP7470-Ag | Bovines/Cattle | Bovines/Cattle MMADHC recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP7470-Ag | Equine/Horse | Equine/Horse MMADHC recombinant protein | Mammalian cell | Detail |
