Recombinant multi-species FUS/TLS protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FUS/TLS protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6. [provided by RefSeq, Sep 2009]
The Alternative Names of target: 75 kDa DNA-pairing protein,ALS6,D430004D17Rik,D930039C12Rik,ETM4,FUS,FUS1,Fus,Fus1,HNRNPP2,Oncogene FUS,Oncogene TLS,POMP75,POMp75,RNA-binding protein FUS,TLS,Tls,Translocated in liposarcoma protein,altFUS

Target products collectionGo to FUS/TLS products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP7009-Ag-1/ GM-Tg-hg-IP7009-Ag-2 Human FUS/TLS protein Human
GM-Tg-rg-IP7009-Ag-1/ GM-Tg-rg-IP7009-Ag-2 Rat FUS/TLS protein Rat
GM-Tg-mg-IP7009-Ag-1/ GM-Tg-mg-IP7009-Ag-2 Mouse FUS/TLS protein Mouse
GM-Tg-cynog-IP7009-Ag-1/ GM-Tg-cynog-IP7009-Ag-2 Cynomolgus/Rhesus macaque FUS/TLS protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP7009-Ag-1/ GM-Tg-felg-IP7009-Ag-2 Feline FUS/TLS protein Feline
GM-Tg-cang-IP7009-Ag-1/ GM-Tg-cang-IP7009-Ag-2 Canine FUS/TLS protein Canine
GM-Tg-bovg-IP7009-Ag-1/ GM-Tg-bovg-IP7009-Ag-2 Bovine FUS/TLS protein Bovine
GM-Tg-equg-IP7009-Ag-1/ GM-Tg-equg-IP7009-Ag-2 Equine FUS/TLS protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP7009-Ag-1/ GM-Tg-hg-IP7009-Ag-2; GM-Tg-rg-IP7009-Ag-1/ GM-Tg-rg-IP7009-Ag-2;
GM-Tg-mg-IP7009-Ag-1/ GM-Tg-mg-IP7009-Ag-2; GM-Tg-cynog-IP7009-Ag-1/ GM-Tg-cynog-IP7009-Ag-2;
GM-Tg-felg-IP7009-Ag-1/ GM-Tg-felg-IP7009-Ag-2; GM-Tg-cang-IP7009-Ag-1/ GM-Tg-cang-IP7009-Ag-2;
GM-Tg-bovg-IP7009-Ag-1/ GM-Tg-bovg-IP7009-Ag-2; GM-Tg-equg-IP7009-Ag-1/ GM-Tg-equg-IP7009-Ag-2
Products Name FUS/TLS protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name FUS/TLS
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FUS/TLS protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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