Explore FUS/TLS gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6. [provided by RefSeq, Sep 2009]
| Target ID |
GM-IP7009
|
| Target Name |
FUS/TLS
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2521
|
| Gene ID |
100063286 (Equus caballus), 100856381 (Canis lupus familiaris), 101088901 (Felis catus), 233908 (Mus musculus)
2521 (Homo sapiens), 280796 (Bos taurus), 317385 (Rattus norvegicus), 713433 (Macaca mulatta)
|
| Target Alternative Names |
75 kDa DNA-pairing protein,ALS6,D430004D17Rik,D930039C12Rik,ETM4,FUS,FUS1,Fus,Fus1,HNRNPP2,Oncogene FUS,Oncogene TLS,POMP75,POMp75,RNA-binding protein FUS,TLS,Tls,Translocated in liposarcoma protein,altFUS
|
| Uniprot Accession |
P56959,P35637,Q28009
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Disease |
cancer
|
| Disease from KEGG |
|
| Gene Ensembl |
ENSECAG00000036779, ENSCAFG00845011986, ENSMUSG00000030795, ENSG00000089280, ENSBTAG00000005757, ENSMMUG00000016276
|
| Target Classification |
|
Pre-made viral vector of FUS/TLS cDNA Clones/ORF Plasmid
FUS/TLS siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2521 | Pre-made Human FUS/TLS/ALS6 siRNA oligo Duplex | 2521 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo317385 | Pre-made Rat Fus siRNA oligo Duplex | 317385 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo233908 | Pre-made Mouse Fus/Tls/Fus1 siRNA oligo Duplex | 233908 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo713433 | Pre-made Cynomolgus/Rhesus macaque FUS siRNA oligo Duplex | 713433 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101088901 | Pre-made Cat/Feline FUS siRNA oligo Duplex | 101088901 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100856381 | Pre-made Dog/Canine FUS siRNA oligo Duplex | 100856381 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo280796 | Pre-made Bovines/Cattle FUS siRNA oligo Duplex | 280796 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100063286 | Pre-made Equine/Horse FUS siRNA oligo Duplex | 100063286 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
FUS/TLS antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP7009-Ab | Human | Anti-Human FUS/TLS monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP7009-Ab | Rat | Anti-Rat FUS/TLS monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP7009-Ab | Mouse | Anti-Mouse FUS/TLS monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP7009-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque FUS/TLS monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP7009-Ab | Cat/Feline | Anti-Cat/Feline FUS/TLS monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP7009-Ab | Dog/Canine | Anti-Dog/Canine FUS/TLS monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP7009-Ab | Bovines/Cattle | Anti-Bovines/Cattle FUS/TLS monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP7009-Ab | Equine/Horse | Anti-Equine/Horse FUS/TLS monoclonal antibody | mab | | Detail |
FUS/TLS recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP7009-Ag | Human | Human FUS/TLS recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP7009-Ag | Rat | Rat FUS/TLS recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP7009-Ag | Mouse | Mouse FUS/TLS recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP7009-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque FUS/TLS recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP7009-Ag | Cat/Feline | Cat/Feline FUS/TLS recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP7009-Ag | Dog/Canine | Dog/Canine FUS/TLS recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP7009-Ag | Bovines/Cattle | Bovines/Cattle FUS/TLS recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP7009-Ag | Equine/Horse | Equine/Horse FUS/TLS recombinant protein | Mammalian cell | Detail |
