Recombinant multi-species SF3B3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SF3B3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 1810061H24Rik,5730409A01Rik,D8Ertd633e,Pre-mRNA-splicing factor SF3b 130 kDa subunit (SF3b130),RSE1,SAP130,SF3B3,SF3b130,STAF130,Sf3b3,Spliceosome-associated protein 130 (SAP 130),Splicing factor 3B subunit 3,mKIAA0017

Target products collectionGo to SF3B3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP6888-Ag-1/ GM-Tg-hg-IP6888-Ag-2 Human SF3B3 protein Human
GM-Tg-rg-IP6888-Ag-1/ GM-Tg-rg-IP6888-Ag-2 Rat SF3B3 protein Rat
GM-Tg-mg-IP6888-Ag-1/ GM-Tg-mg-IP6888-Ag-2 Mouse SF3B3 protein Mouse
GM-Tg-cynog-IP6888-Ag-1/ GM-Tg-cynog-IP6888-Ag-2 Cynomolgus/Rhesus macaque SF3B3 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP6888-Ag-1/ GM-Tg-felg-IP6888-Ag-2 Feline SF3B3 protein Feline
GM-Tg-cang-IP6888-Ag-1/ GM-Tg-cang-IP6888-Ag-2 Canine SF3B3 protein Canine
GM-Tg-bovg-IP6888-Ag-1/ GM-Tg-bovg-IP6888-Ag-2 Bovine SF3B3 protein Bovine
GM-Tg-equg-IP6888-Ag-1/ GM-Tg-equg-IP6888-Ag-2 Equine SF3B3 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP6888-Ag-1/ GM-Tg-hg-IP6888-Ag-2; GM-Tg-rg-IP6888-Ag-1/ GM-Tg-rg-IP6888-Ag-2;
GM-Tg-mg-IP6888-Ag-1/ GM-Tg-mg-IP6888-Ag-2; GM-Tg-cynog-IP6888-Ag-1/ GM-Tg-cynog-IP6888-Ag-2;
GM-Tg-felg-IP6888-Ag-1/ GM-Tg-felg-IP6888-Ag-2; GM-Tg-cang-IP6888-Ag-1/ GM-Tg-cang-IP6888-Ag-2;
GM-Tg-bovg-IP6888-Ag-1/ GM-Tg-bovg-IP6888-Ag-2; GM-Tg-equg-IP6888-Ag-1/ GM-Tg-equg-IP6888-Ag-2
Products Name SF3B3 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name SF3B3
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SF3B3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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