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Target
sublocation: Introcelluar Protein.
This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair. [provided by RefSeq, Jul 2008]
| Target ID |
GM-IP6888
|
| Target Name |
SF3B3
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
23450
|
| Gene ID |
100054753 (Equus caballus), 101086362 (Felis catus), 101943 (Mus musculus), 23450 (Homo sapiens) 292019 (Rattus norvegicus), 479659 (Canis lupus familiaris), 504962 (Bos taurus), 708939 (Macaca mulatta)
|
| Target Alternative Names |
1810061H24Rik,5730409A01Rik,D8Ertd633e,Pre-mRNA-splicing factor SF3b 130 kDa subunit (SF3b130),RSE1,SAP130,SF3B3,SF3b130,STAF130,Sf3b3,Spliceosome-associated protein 130 (SAP 130),Splicing factor 3B subunit 3,mKIAA0017
|
| Uniprot Accession |
Q921M3,Q15393,A0JN52
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000014053, ENSMUSG00000033732, ENSG00000189091, ENSCAFG00845005230, ENSBTAG00000010627, ENSMMUG00000017812
|
SF3B3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo23450 | Pre-made Human SF3B3/RSE1/SAP130 siRNA oligo Duplex | 23450 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo292019 | Pre-made Rat Sf3b3 siRNA oligo Duplex | 292019 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101943 | Pre-made Mouse Sf3b3/RSE1/SAP130 siRNA oligo Duplex | 101943 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo708939 | Pre-made Cynomolgus/Rhesus macaque SF3B3 siRNA oligo Duplex | 708939 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101086362 | Pre-made Cat/Feline SF3B3 siRNA oligo Duplex | 101086362 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo479659 | Pre-made Dog/Canine SF3B3 siRNA oligo Duplex | 479659 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo504962 | Pre-made Bovines/Cattle SF3B3 siRNA oligo Duplex | 504962 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100054753 | Pre-made Equine/Horse SF3B3 siRNA oligo Duplex | 100054753 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
SF3B3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP6888-Ab | Human | Anti-Human SF3B3 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP6888-Ab | Rat | Anti-Rat SF3B3 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP6888-Ab | Mouse | Anti-Mouse SF3B3 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP6888-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque SF3B3 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP6888-Ab | Cat/Feline | Anti-Cat/Feline SF3B3 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP6888-Ab | Dog/Canine | Anti-Dog/Canine SF3B3 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP6888-Ab | Bovines/Cattle | Anti-Bovines/Cattle SF3B3 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP6888-Ab | Equine/Horse | Anti-Equine/Horse SF3B3 monoclonal antibody | mab | | Detail |
SF3B3 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP6888-Ag | Human | Human SF3B3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP6888-Ag | Rat | Rat SF3B3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP6888-Ag | Mouse | Mouse SF3B3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP6888-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque SF3B3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP6888-Ag | Cat/Feline | Cat/Feline SF3B3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP6888-Ag | Dog/Canine | Dog/Canine SF3B3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP6888-Ag | Bovines/Cattle | Bovines/Cattle SF3B3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP6888-Ag | Equine/Horse | Equine/Horse SF3B3 recombinant protein | Mammalian cell | Detail |