Recombinant multi-species FMR1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FMR1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. [provided by RefSeq, May 2010]
The Alternative Names of target: FMR1,FMRP,FRAXA,Fmr-1,Fmr1,Fragile X messenger ribonucleoprotein (FMRP),Fragile X messenger ribonucleoprotein 1,POF,POF1,Protein FMR-1

Target products collectionGo to FMR1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP6829-Ag-1/ GM-Tg-hg-IP6829-Ag-2 Human FMR1 protein Human
GM-Tg-rg-IP6829-Ag-1/ GM-Tg-rg-IP6829-Ag-2 Rat FMR1 protein Rat
GM-Tg-mg-IP6829-Ag-1/ GM-Tg-mg-IP6829-Ag-2 Mouse FMR1 protein Mouse
GM-Tg-cynog-IP6829-Ag-1/ GM-Tg-cynog-IP6829-Ag-2 Cynomolgus/Rhesus macaque FMR1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP6829-Ag-1/ GM-Tg-felg-IP6829-Ag-2 Feline FMR1 protein Feline
GM-Tg-cang-IP6829-Ag-1/ GM-Tg-cang-IP6829-Ag-2 Canine FMR1 protein Canine
GM-Tg-bovg-IP6829-Ag-1/ GM-Tg-bovg-IP6829-Ag-2 Bovine FMR1 protein Bovine
GM-Tg-equg-IP6829-Ag-1/ GM-Tg-equg-IP6829-Ag-2 Equine FMR1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP6829-Ag-1/ GM-Tg-hg-IP6829-Ag-2; GM-Tg-rg-IP6829-Ag-1/ GM-Tg-rg-IP6829-Ag-2;
GM-Tg-mg-IP6829-Ag-1/ GM-Tg-mg-IP6829-Ag-2; GM-Tg-cynog-IP6829-Ag-1/ GM-Tg-cynog-IP6829-Ag-2;
GM-Tg-felg-IP6829-Ag-1/ GM-Tg-felg-IP6829-Ag-2; GM-Tg-cang-IP6829-Ag-1/ GM-Tg-cang-IP6829-Ag-2;
GM-Tg-bovg-IP6829-Ag-1/ GM-Tg-bovg-IP6829-Ag-2; GM-Tg-equg-IP6829-Ag-1/ GM-Tg-equg-IP6829-Ag-2
Products Name FMR1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name FMR1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FMR1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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