Explore FMR1 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. [provided by RefSeq, May 2010]
| Target ID |
GM-IP6829
|
| Target Name |
FMR1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
2332
|
| Gene ID |
101080266 (Felis catus), 111771604 (Equus caballus), 14265 (Mus musculus), 2332 (Homo sapiens) 24948 (Rattus norvegicus), 481070 (Canis lupus familiaris), 507482 (Bos taurus), 700138 (Macaca mulatta)
|
| Target Alternative Names |
FMR1,FMRP,FRAXA,Fmr-1,Fmr1,Fragile X messenger ribonucleoprotein (FMRP),Fragile X messenger ribonucleoprotein 1,POF,POF1,Protein FMR-1
|
| Uniprot Accession |
P35922,Q06787,Q80WE1
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000032767, ENSMUSG00000000838, ENSG00000102081, ENSCAFG00845020694, ENSBTAG00000012552, ENSMMUG00000015814
|
Pre-made viral vector of FMR1 cDNA Clones/ORF Plasmid
FMR1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2332 | Pre-made Human FMR1/POF/FMRP siRNA oligo Duplex | 2332 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24948 | Pre-made Rat Fmr1/FMRP siRNA oligo Duplex | 24948 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14265 | Pre-made Mouse Fmr1/FMRP/Fmr-1 siRNA oligo Duplex | 14265 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo700138 | Pre-made Cynomolgus/Rhesus macaque FMR1 siRNA oligo Duplex | 700138 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101080266 | Pre-made Cat/Feline FMR1 siRNA oligo Duplex | 101080266 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo481070 | Pre-made Dog/Canine FMR1 siRNA oligo Duplex | 481070 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo507482 | Pre-made Bovines/Cattle FMR1 siRNA oligo Duplex | 507482 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo111771604 | Pre-made Equine/Horse FMR1 siRNA oligo Duplex | 111771604 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
FMR1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP6829-Ab | Human | Anti-Human FMR1 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP6829-Ab | Rat | Anti-Rat FMR1 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP6829-Ab | Mouse | Anti-Mouse FMR1 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP6829-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque FMR1 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP6829-Ab | Cat/Feline | Anti-Cat/Feline FMR1 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP6829-Ab | Dog/Canine | Anti-Dog/Canine FMR1 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP6829-Ab | Bovines/Cattle | Anti-Bovines/Cattle FMR1 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP6829-Ab | Equine/Horse | Anti-Equine/Horse FMR1 monoclonal antibody | mab | | Detail |
FMR1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP6829-Ag | Human | Human FMR1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP6829-Ag | Rat | Rat FMR1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP6829-Ag | Mouse | Mouse FMR1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP6829-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque FMR1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP6829-Ag | Cat/Feline | Cat/Feline FMR1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP6829-Ag | Dog/Canine | Dog/Canine FMR1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP6829-Ag | Bovines/Cattle | Bovines/Cattle FMR1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP6829-Ag | Equine/Horse | Equine/Horse FMR1 recombinant protein | Mammalian cell | Detail |