Recombinant multi-species FOXG1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FOXG1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This locus encodes a member of the fork-head transcription factor family. The encoded protein, which functions as a transcriptional repressor, is highly expressed in neural tissues during brain development. Mutations at this locus have been associated with Rett syndrome and a diverse spectrum of neurodevelopmental disorders defined as part of the FOXG1 syndrome. This gene is disregulated in many types of cancer and is the target of multiple microRNAs that regulate the proliferation of tumor cells. [provided by RefSeq, Jul 2020]
The Alternative Names of target: 2900064B05Rik,BF-1,BF1,BF1),BF1A,BF2,Bf1,Brain factor 1 (BF-1,Brain factor 2 (BF-2,FHKL3,FKH2,FKHL1,FKHL2,FKHL3,FKHL4,FOXG1,FOXG1A,FOXG1B,FOXG1C,Fkhl1,Forkhead box protein G1,Forkhead box protein G1A,Forkhead box protein G1B,Forkhead box protein G1C,Forkhead-related protein FKHL1 (HFK1),Forkhead-related protein FKHL2 (HFK2),Forkhead-related protein FKHL3 (HFK3),Foxg1,HBF-1,HBF-2,HBF-3,HBF-G2,HBF2,HFK1,HFK2,HFK3,Hfh9,Hfhbf1,KHL2,QIN,RATBF1A,hBF-2)
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP6625-Ag-1/ GM-Tg-hg-IP6625-Ag-2 | Human FOXG1 protein | Human |
| GM-Tg-rg-IP6625-Ag-1/ GM-Tg-rg-IP6625-Ag-2 | Rat FOXG1 protein | Rat |
| GM-Tg-mg-IP6625-Ag-1/ GM-Tg-mg-IP6625-Ag-2 | Mouse FOXG1 protein | Mouse |
| GM-Tg-cynog-IP6625-Ag-1/ GM-Tg-cynog-IP6625-Ag-2 | Cynomolgus/Rhesus macaque FOXG1 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP6625-Ag-1/ GM-Tg-felg-IP6625-Ag-2 | Feline FOXG1 protein | Feline |
| GM-Tg-cang-IP6625-Ag-1/ GM-Tg-cang-IP6625-Ag-2 | Canine FOXG1 protein | Canine |
| GM-Tg-bovg-IP6625-Ag-1/ GM-Tg-bovg-IP6625-Ag-2 | Bovine FOXG1 protein | Bovine |
| GM-Tg-equg-IP6625-Ag-1/ GM-Tg-equg-IP6625-Ag-2 | Equine FOXG1 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP6625-Ag-1/ GM-Tg-hg-IP6625-Ag-2;
GM-Tg-rg-IP6625-Ag-1/ GM-Tg-rg-IP6625-Ag-2;
GM-Tg-mg-IP6625-Ag-1/ GM-Tg-mg-IP6625-Ag-2; GM-Tg-cynog-IP6625-Ag-1/ GM-Tg-cynog-IP6625-Ag-2; GM-Tg-felg-IP6625-Ag-1/ GM-Tg-felg-IP6625-Ag-2; GM-Tg-cang-IP6625-Ag-1/ GM-Tg-cang-IP6625-Ag-2; GM-Tg-bovg-IP6625-Ag-1/ GM-Tg-bovg-IP6625-Ag-2; GM-Tg-equg-IP6625-Ag-1/ GM-Tg-equg-IP6625-Ag-2 |
| Products Name | FOXG1 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | FOXG1 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FOXG1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.