Recombinant multi-species FANCD2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FANCD2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group D2. This protein is monoubiquinated in response to DNA damage, resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homology-directed DNA repair. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
The Alternative Names of target: 2410150O07Rik,FA-D2,FA4,FACD,FAD,FAD2,FANCD,FANCD2,Fancd2,Fanconi anemia group D2 protein,Protein FACD2

Target products collectionGo to FANCD2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP6455-Ag-1/ GM-Tg-hg-IP6455-Ag-2 Human FANCD2 protein Human
GM-Tg-rg-IP6455-Ag-1/ GM-Tg-rg-IP6455-Ag-2 Rat FANCD2 protein Rat
GM-Tg-mg-IP6455-Ag-1/ GM-Tg-mg-IP6455-Ag-2 Mouse FANCD2 protein Mouse
GM-Tg-cynog-IP6455-Ag-1/ GM-Tg-cynog-IP6455-Ag-2 Cynomolgus/Rhesus macaque FANCD2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP6455-Ag-1/ GM-Tg-felg-IP6455-Ag-2 Feline FANCD2 protein Feline
GM-Tg-cang-IP6455-Ag-1/ GM-Tg-cang-IP6455-Ag-2 Canine FANCD2 protein Canine
GM-Tg-bovg-IP6455-Ag-1/ GM-Tg-bovg-IP6455-Ag-2 Bovine FANCD2 protein Bovine
GM-Tg-equg-IP6455-Ag-1/ GM-Tg-equg-IP6455-Ag-2 Equine FANCD2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP6455-Ag-1/ GM-Tg-hg-IP6455-Ag-2; GM-Tg-rg-IP6455-Ag-1/ GM-Tg-rg-IP6455-Ag-2;
GM-Tg-mg-IP6455-Ag-1/ GM-Tg-mg-IP6455-Ag-2; GM-Tg-cynog-IP6455-Ag-1/ GM-Tg-cynog-IP6455-Ag-2;
GM-Tg-felg-IP6455-Ag-1/ GM-Tg-felg-IP6455-Ag-2; GM-Tg-cang-IP6455-Ag-1/ GM-Tg-cang-IP6455-Ag-2;
GM-Tg-bovg-IP6455-Ag-1/ GM-Tg-bovg-IP6455-Ag-2; GM-Tg-equg-IP6455-Ag-1/ GM-Tg-equg-IP6455-Ag-2
Products Name FANCD2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name FANCD2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FANCD2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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