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Target
sublocation: Introcelluar Protein.
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group D2. This protein is monoubiquinated in response to DNA damage, resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homology-directed DNA repair. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
| Target ID |
GM-IP6455
|
| Target Name |
FANCD2
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
2177
|
| Gene ID |
100051871 (Equus caballus), 101092341 (Felis catus), 211651 (Mus musculus), 2177 (Homo sapiens) 312641 (Rattus norvegicus), 484659 (Canis lupus familiaris), 515845 (Bos taurus)
|
| Target Alternative Names |
2410150O07Rik,FA-D2,FA4,FACD,FAD,FAD2,FANCD,FANCD2,Fancd2,Fanconi anemia group D2 protein,Protein FACD2
|
| Uniprot Accession |
Q80V62,Q9BXW9,Q6IV68
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000018519, ENSMUSG00000034023, ENSG00000144554, ENSCAFG00845008276, ENSBTAG00000010077
|
FANCD2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2177 | Pre-made Human FANCD2/FA4/FAD siRNA oligo Duplex | 2177 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo312641 | Pre-made Rat Fancd2 siRNA oligo Duplex | 312641 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo211651 | Pre-made Mouse Fancd2/FA4/FAD siRNA oligo Duplex | 211651 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101092341 | Pre-made Cat/Feline FANCD2 siRNA oligo Duplex | 101092341 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo484659 | Pre-made Dog/Canine FANCD2 siRNA oligo Duplex | 484659 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo515845 | Pre-made Bovines/Cattle FANCD2 siRNA oligo Duplex | 515845 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100051871 | Pre-made Equine/Horse FANCD2 siRNA oligo Duplex | 100051871 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
FANCD2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP6455-Ab | Human | Anti-Human FANCD2 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP6455-Ab | Rat | Anti-Rat FANCD2 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP6455-Ab | Mouse | Anti-Mouse FANCD2 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP6455-Ab | Cat/Feline | Anti-Cat/Feline FANCD2 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP6455-Ab | Dog/Canine | Anti-Dog/Canine FANCD2 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP6455-Ab | Bovines/Cattle | Anti-Bovines/Cattle FANCD2 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP6455-Ab | Equine/Horse | Anti-Equine/Horse FANCD2 monoclonal antibody | mab | | Detail |
FANCD2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP6455-Ag | Human | Human FANCD2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP6455-Ag | Rat | Rat FANCD2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP6455-Ag | Mouse | Mouse FANCD2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP6455-Ag | Cat/Feline | Cat/Feline FANCD2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP6455-Ag | Dog/Canine | Dog/Canine FANCD2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP6455-Ag | Bovines/Cattle | Bovines/Cattle FANCD2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP6455-Ag | Equine/Horse | Equine/Horse FANCD2 recombinant protein | Mammalian cell | Detail |