Recombinant multi-species EVI1/MECOM protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine EVI1/MECOM protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
The Alternative Names of target: AML1-EVI-1,D630039M04Rik,EVI1,Ecotropic virus integration site 1 protein homolog (EVI-1),Evi-1,Evi1,Histone-lysine N-methyltransferase MECOM,Jbo,KMT8E,MDS1,MDS1 and EVI1 complex locus protein,MDS1-EVI1,MECOM,Mds,Mds1,Mds1-Evi1,Mecom,Myelodysplasia syndrome 1 protein,Myelodysplasia syndrome-associated protein 1,PRDM3,Prdm3,RUSAT2,Znfpr1b1

Target products collectionGo to EVI1/MECOM products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP6446-Ag-1/ GM-Tg-hg-IP6446-Ag-2 Human EVI1/MECOM protein Human
GM-Tg-rg-IP6446-Ag-1/ GM-Tg-rg-IP6446-Ag-2 Rat EVI1/MECOM protein Rat
GM-Tg-mg-IP6446-Ag-1/ GM-Tg-mg-IP6446-Ag-2 Mouse EVI1/MECOM protein Mouse
GM-Tg-cynog-IP6446-Ag-1/ GM-Tg-cynog-IP6446-Ag-2 Cynomolgus/Rhesus macaque EVI1/MECOM protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP6446-Ag-1/ GM-Tg-felg-IP6446-Ag-2 Feline EVI1/MECOM protein Feline
GM-Tg-cang-IP6446-Ag-1/ GM-Tg-cang-IP6446-Ag-2 Canine EVI1/MECOM protein Canine
GM-Tg-bovg-IP6446-Ag-1/ GM-Tg-bovg-IP6446-Ag-2 Bovine EVI1/MECOM protein Bovine
GM-Tg-equg-IP6446-Ag-1/ GM-Tg-equg-IP6446-Ag-2 Equine EVI1/MECOM protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP6446-Ag-1/ GM-Tg-hg-IP6446-Ag-2; GM-Tg-rg-IP6446-Ag-1/ GM-Tg-rg-IP6446-Ag-2;
GM-Tg-mg-IP6446-Ag-1/ GM-Tg-mg-IP6446-Ag-2; GM-Tg-cynog-IP6446-Ag-1/ GM-Tg-cynog-IP6446-Ag-2;
GM-Tg-felg-IP6446-Ag-1/ GM-Tg-felg-IP6446-Ag-2; GM-Tg-cang-IP6446-Ag-1/ GM-Tg-cang-IP6446-Ag-2;
GM-Tg-bovg-IP6446-Ag-1/ GM-Tg-bovg-IP6446-Ag-2; GM-Tg-equg-IP6446-Ag-1/ GM-Tg-equg-IP6446-Ag-2
Products Name EVI1/MECOM protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name EVI1/MECOM
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine EVI1/MECOM protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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