Explore EVI1/MECOM gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
| Target ID |
GM-IP6446
|
| Target Name |
EVI1/MECOM
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2122
|
| Gene ID |
100057450 (Equus caballus), 101088775 (Felis catus), 14013 (Mus musculus), 2122 (Homo sapiens)
294924 (Rattus norvegicus), 488148 (Canis lupus familiaris), 532209 (Bos taurus), 698603 (Macaca mulatta)
|
| Target Alternative Names |
AML1-EVI-1,D630039M04Rik,EVI1,Ecotropic virus integration site 1 protein homolog (EVI-1),Evi-1,Evi1,Histone-lysine N-methyltransferase MECOM,Jbo,KMT8E,MDS1,MDS1 and EVI1 complex locus protein,MDS1-EVI1,MECOM,Mds,Mds1,Mds1-Evi1,Mecom,Myelodysplasia syndrome 1 protein,Myelodysplasia syndrome-associated protein 1,PRDM3,Prdm3,RUSAT2,Znfpr1b1
|
| Uniprot Accession |
P14404,Q03112
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000020788, ENSMUSG00000027684, ENSG00000085276, ENSCAFG00845020246, ENSBTAG00000005871, ENSMMUG00000002242
|
Pre-made viral vector of EVI1/MECOM cDNA Clones/ORF Plasmid
EVI1/MECOM siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2122 | Pre-made Human MECOM/EVI1/MDS1 siRNA oligo Duplex | 2122 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo294924 | Pre-made Rat Mecom/Evi1/Mds1 siRNA oligo Duplex | 294924 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14013 | Pre-made Mouse Mecom/Jbo/Mds siRNA oligo Duplex | 14013 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo698603 | Pre-made Cynomolgus/Rhesus macaque MECOM/EVI1 siRNA oligo Duplex | 698603 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101088775 | Pre-made Cat/Feline MECOM siRNA oligo Duplex | 101088775 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo488148 | Pre-made Dog/Canine MECOM/EVI1 siRNA oligo Duplex | 488148 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo532209 | Pre-made Bovines/Cattle MECOM/EVI1 siRNA oligo Duplex | 532209 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100057450 | Pre-made Equine/Horse MECOM siRNA oligo Duplex | 100057450 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
EVI1/MECOM antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP6446-Ab | Human | Anti-Human EVI1/MECOM monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP6446-Ab | Rat | Anti-Rat EVI1/MECOM monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP6446-Ab | Mouse | Anti-Mouse EVI1/MECOM monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP6446-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque EVI1/MECOM monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP6446-Ab | Cat/Feline | Anti-Cat/Feline EVI1/MECOM monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP6446-Ab | Dog/Canine | Anti-Dog/Canine EVI1/MECOM monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP6446-Ab | Bovines/Cattle | Anti-Bovines/Cattle EVI1/MECOM monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP6446-Ab | Equine/Horse | Anti-Equine/Horse EVI1/MECOM monoclonal antibody | mab | | Detail |
EVI1/MECOM recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP6446-Ag | Human | Human EVI1/MECOM recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP6446-Ag | Rat | Rat EVI1/MECOM recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP6446-Ag | Mouse | Mouse EVI1/MECOM recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP6446-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque EVI1/MECOM recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP6446-Ag | Cat/Feline | Cat/Feline EVI1/MECOM recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP6446-Ag | Dog/Canine | Dog/Canine EVI1/MECOM recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP6446-Ag | Bovines/Cattle | Bovines/Cattle EVI1/MECOM recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP6446-Ag | Equine/Horse | Equine/Horse EVI1/MECOM recombinant protein | Mammalian cell | Detail |
