Recombinant multi-species eIF4G2/DAP5/EIF4G2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine eIF4G2/DAP5/EIF4G2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008]
The Alternative Names of target: AAG1,DAP-5,DAP5,Death-associated protein 5 (DAP-5),E130105L11Rik,EIF4G2,Eif4g2,Eukaryotic translation initiation factor 4 gamma 2,NAT1,Nat1,Natm1,P97,eIF-4-gamma 2,eIF-4G 2,eIF4G 2,eIF4G2,p97

Target products collectionGo to eIF4G2/DAP5/EIF4G2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP6317-Ag-1/ GM-Tg-hg-IP6317-Ag-2 Human eIF4G2/DAP5/EIF4G2 protein Human
GM-Tg-rg-IP6317-Ag-1/ GM-Tg-rg-IP6317-Ag-2 Rat eIF4G2/DAP5/EIF4G2 protein Rat
GM-Tg-mg-IP6317-Ag-1/ GM-Tg-mg-IP6317-Ag-2 Mouse eIF4G2/DAP5/EIF4G2 protein Mouse
GM-Tg-cynog-IP6317-Ag-1/ GM-Tg-cynog-IP6317-Ag-2 Cynomolgus/Rhesus macaque eIF4G2/DAP5/EIF4G2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP6317-Ag-1/ GM-Tg-felg-IP6317-Ag-2 Feline eIF4G2/DAP5/EIF4G2 protein Feline
GM-Tg-cang-IP6317-Ag-1/ GM-Tg-cang-IP6317-Ag-2 Canine eIF4G2/DAP5/EIF4G2 protein Canine
GM-Tg-bovg-IP6317-Ag-1/ GM-Tg-bovg-IP6317-Ag-2 Bovine eIF4G2/DAP5/EIF4G2 protein Bovine
GM-Tg-equg-IP6317-Ag-1/ GM-Tg-equg-IP6317-Ag-2 Equine eIF4G2/DAP5/EIF4G2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP6317-Ag-1/ GM-Tg-hg-IP6317-Ag-2; GM-Tg-rg-IP6317-Ag-1/ GM-Tg-rg-IP6317-Ag-2;
GM-Tg-mg-IP6317-Ag-1/ GM-Tg-mg-IP6317-Ag-2; GM-Tg-cynog-IP6317-Ag-1/ GM-Tg-cynog-IP6317-Ag-2;
GM-Tg-felg-IP6317-Ag-1/ GM-Tg-felg-IP6317-Ag-2; GM-Tg-cang-IP6317-Ag-1/ GM-Tg-cang-IP6317-Ag-2;
GM-Tg-bovg-IP6317-Ag-1/ GM-Tg-bovg-IP6317-Ag-2; GM-Tg-equg-IP6317-Ag-1/ GM-Tg-equg-IP6317-Ag-2
Products Name eIF4G2/DAP5/EIF4G2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name eIF4G2/DAP5/EIF4G2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine eIF4G2/DAP5/EIF4G2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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