Recombinant multi-species EIF4G1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine EIF4G1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. [provided by RefSeq, Aug 2010]
The Alternative Names of target: E030015G23Rik,EIF-4G1,EIF4F,EIF4G,EIF4G1,EIF4GI,Eif4g1,Eukaryotic translation initiation factor 4 gamma 1,P220,PARK18,eIF-4-gamma 1,eIF-4G 1,eIF-4G1,eIF4GI,p220

Target products collectionGo to EIF4G1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP6316-Ag-1/ GM-Tg-hg-IP6316-Ag-2 Human EIF4G1 protein Human
GM-Tg-rg-IP6316-Ag-1/ GM-Tg-rg-IP6316-Ag-2 Rat EIF4G1 protein Rat
GM-Tg-mg-IP6316-Ag-1/ GM-Tg-mg-IP6316-Ag-2 Mouse EIF4G1 protein Mouse
GM-Tg-cynog-IP6316-Ag-1/ GM-Tg-cynog-IP6316-Ag-2 Cynomolgus/Rhesus macaque EIF4G1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP6316-Ag-1/ GM-Tg-felg-IP6316-Ag-2 Feline EIF4G1 protein Feline
GM-Tg-cang-IP6316-Ag-1/ GM-Tg-cang-IP6316-Ag-2 Canine EIF4G1 protein Canine
GM-Tg-bovg-IP6316-Ag-1/ GM-Tg-bovg-IP6316-Ag-2 Bovine EIF4G1 protein Bovine
GM-Tg-equg-IP6316-Ag-1/ GM-Tg-equg-IP6316-Ag-2 Equine EIF4G1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP6316-Ag-1/ GM-Tg-hg-IP6316-Ag-2; GM-Tg-rg-IP6316-Ag-1/ GM-Tg-rg-IP6316-Ag-2;
GM-Tg-mg-IP6316-Ag-1/ GM-Tg-mg-IP6316-Ag-2; GM-Tg-cynog-IP6316-Ag-1/ GM-Tg-cynog-IP6316-Ag-2;
GM-Tg-felg-IP6316-Ag-1/ GM-Tg-felg-IP6316-Ag-2; GM-Tg-cang-IP6316-Ag-1/ GM-Tg-cang-IP6316-Ag-2;
GM-Tg-bovg-IP6316-Ag-1/ GM-Tg-bovg-IP6316-Ag-2; GM-Tg-equg-IP6316-Ag-1/ GM-Tg-equg-IP6316-Ag-2
Products Name EIF4G1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name EIF4G1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine EIF4G1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.