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Target
sublocation: Introcelluar Protein.
The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. [provided by RefSeq, Aug 2010]
| Target ID |
GM-IP6316
|
| Target Name |
EIF4G1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
1981
|
| Gene ID |
100033975 (Equus caballus), 100688785 (Canis lupus familiaris), 101085654 (Felis catus), 1981 (Homo sapiens) 208643 (Mus musculus), 287986 (Rattus norvegicus), 444858 (Bos taurus), 704923 (Macaca mulatta)
|
| Target Alternative Names |
E030015G23Rik,EIF-4G1,EIF4F,EIF4G,EIF4G1,EIF4GI,Eif4g1,Eukaryotic translation initiation factor 4 gamma 1,P220,PARK18,eIF-4-gamma 1,eIF-4G 1,eIF-4G1,eIF4GI,p220
|
| Uniprot Accession |
Q04637,Q6NZJ6
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000008046, ENSCAFG00845027677, ENSG00000114867, ENSMUSG00000045983, ENSBTAG00000012881, ENSMMUG00000010934
|
EIF4G1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1981 | Pre-made Human EIF4G1/P220/EIF4F siRNA oligo Duplex | 1981 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo287986 | Pre-made Rat Eif4g1 siRNA oligo Duplex | 287986 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo208643 | Pre-made Mouse Eif4g1/eIF4GI/eIF-4G1 siRNA oligo Duplex | 208643 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo704923 | Pre-made Cynomolgus/Rhesus macaque EIF4G1 siRNA oligo Duplex | 704923 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101085654 | Pre-made Cat/Feline EIF4G1 siRNA oligo Duplex | 101085654 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100688785 | Pre-made Dog/Canine EIF4G1 siRNA oligo Duplex | 100688785 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo444858 | Pre-made Bovines/Cattle EIF4G1/EIF4GI siRNA oligo Duplex | 444858 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100033975 | Pre-made Equine/Horse EIF4G1/EIF4GI siRNA oligo Duplex | 100033975 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
EIF4G1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP6316-Ab | Human | Anti-Human EIF4G1 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP6316-Ab | Rat | Anti-Rat EIF4G1 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP6316-Ab | Mouse | Anti-Mouse EIF4G1 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP6316-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque EIF4G1 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP6316-Ab | Cat/Feline | Anti-Cat/Feline EIF4G1 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP6316-Ab | Dog/Canine | Anti-Dog/Canine EIF4G1 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP6316-Ab | Bovines/Cattle | Anti-Bovines/Cattle EIF4G1 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP6316-Ab | Equine/Horse | Anti-Equine/Horse EIF4G1 monoclonal antibody | mab | | Detail |
EIF4G1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP6316-Ag | Human | Human EIF4G1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP6316-Ag | Rat | Rat EIF4G1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP6316-Ag | Mouse | Mouse EIF4G1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP6316-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque EIF4G1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP6316-Ag | Cat/Feline | Cat/Feline EIF4G1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP6316-Ag | Dog/Canine | Dog/Canine EIF4G1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP6316-Ag | Bovines/Cattle | Bovines/Cattle EIF4G1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP6316-Ag | Equine/Horse | Equine/Horse EIF4G1 recombinant protein | Mammalian cell | Detail |