Recombinant multi-species CYB5R3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CYB5R3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in this gene cause methemoglobinemias. [provided by RefSeq, Jan 2010]
The Alternative Names of target: 0610016L08Rik,2500002N19Rik,B5R,C5BR,CB5R,CYB5R3,Cyb5r3,Cytochrome b5 reductase,DIA1,Dia-1,Dia1,Diaphorase-1,NADH-cytochrome b5 reductase 3,Nadhcb5,RNNADHCB5,WU:Cyb5r3

Target products collectionGo to CYB5R3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP6204-Ag-1/ GM-Tg-hg-IP6204-Ag-2 Human CYB5R3 protein Human
GM-Tg-rg-IP6204-Ag-1/ GM-Tg-rg-IP6204-Ag-2 Rat CYB5R3 protein Rat
GM-Tg-mg-IP6204-Ag-1/ GM-Tg-mg-IP6204-Ag-2 Mouse CYB5R3 protein Mouse
GM-Tg-cynog-IP6204-Ag-1/ GM-Tg-cynog-IP6204-Ag-2 Cynomolgus/Rhesus macaque CYB5R3 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP6204-Ag-1/ GM-Tg-felg-IP6204-Ag-2 Feline CYB5R3 protein Feline
GM-Tg-cang-IP6204-Ag-1/ GM-Tg-cang-IP6204-Ag-2 Canine CYB5R3 protein Canine
GM-Tg-bovg-IP6204-Ag-1/ GM-Tg-bovg-IP6204-Ag-2 Bovine CYB5R3 protein Bovine
GM-Tg-equg-IP6204-Ag-1/ GM-Tg-equg-IP6204-Ag-2 Equine CYB5R3 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP6204-Ag-1/ GM-Tg-hg-IP6204-Ag-2; GM-Tg-rg-IP6204-Ag-1/ GM-Tg-rg-IP6204-Ag-2;
GM-Tg-mg-IP6204-Ag-1/ GM-Tg-mg-IP6204-Ag-2; GM-Tg-cynog-IP6204-Ag-1/ GM-Tg-cynog-IP6204-Ag-2;
GM-Tg-felg-IP6204-Ag-1/ GM-Tg-felg-IP6204-Ag-2; GM-Tg-cang-IP6204-Ag-1/ GM-Tg-cang-IP6204-Ag-2;
GM-Tg-bovg-IP6204-Ag-1/ GM-Tg-bovg-IP6204-Ag-2; GM-Tg-equg-IP6204-Ag-1/ GM-Tg-equg-IP6204-Ag-2
Products Name CYB5R3 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name CYB5R3
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CYB5R3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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