Recombinant multi-species CYB5R3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CYB5R3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in this gene cause methemoglobinemias. [provided by RefSeq, Jan 2010]
The Alternative Names of target: 0610016L08Rik,2500002N19Rik,B5R,C5BR,CB5R,CYB5R3,Cyb5r3,Cytochrome b5 reductase,DIA1,Dia-1,Dia1,Diaphorase-1,NADH-cytochrome b5 reductase 3,Nadhcb5,RNNADHCB5,WU:Cyb5r3
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP6204-Ag-1/ GM-Tg-hg-IP6204-Ag-2 | Human CYB5R3 protein | Human |
| GM-Tg-rg-IP6204-Ag-1/ GM-Tg-rg-IP6204-Ag-2 | Rat CYB5R3 protein | Rat |
| GM-Tg-mg-IP6204-Ag-1/ GM-Tg-mg-IP6204-Ag-2 | Mouse CYB5R3 protein | Mouse |
| GM-Tg-cynog-IP6204-Ag-1/ GM-Tg-cynog-IP6204-Ag-2 | Cynomolgus/Rhesus macaque CYB5R3 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP6204-Ag-1/ GM-Tg-felg-IP6204-Ag-2 | Feline CYB5R3 protein | Feline |
| GM-Tg-cang-IP6204-Ag-1/ GM-Tg-cang-IP6204-Ag-2 | Canine CYB5R3 protein | Canine |
| GM-Tg-bovg-IP6204-Ag-1/ GM-Tg-bovg-IP6204-Ag-2 | Bovine CYB5R3 protein | Bovine |
| GM-Tg-equg-IP6204-Ag-1/ GM-Tg-equg-IP6204-Ag-2 | Equine CYB5R3 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP6204-Ag-1/ GM-Tg-hg-IP6204-Ag-2;
GM-Tg-rg-IP6204-Ag-1/ GM-Tg-rg-IP6204-Ag-2;
GM-Tg-mg-IP6204-Ag-1/ GM-Tg-mg-IP6204-Ag-2; GM-Tg-cynog-IP6204-Ag-1/ GM-Tg-cynog-IP6204-Ag-2; GM-Tg-felg-IP6204-Ag-1/ GM-Tg-felg-IP6204-Ag-2; GM-Tg-cang-IP6204-Ag-1/ GM-Tg-cang-IP6204-Ag-2; GM-Tg-bovg-IP6204-Ag-1/ GM-Tg-bovg-IP6204-Ag-2; GM-Tg-equg-IP6204-Ag-1/ GM-Tg-equg-IP6204-Ag-2 |
| Products Name | CYB5R3 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | CYB5R3 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CYB5R3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
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entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.