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Target
sublocation: Introcelluar Protein.
This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in this gene cause methemoglobinemias. [provided by RefSeq, Jan 2010]
| Target ID |
GM-IP6204
|
| Target Name |
CYB5R3
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
1727
|
| Gene ID |
100071050 (Equus caballus), 101091382 (Felis catus), 109754 (Mus musculus), 1727 (Homo sapiens) 25035 (Rattus norvegicus), 474479 (Canis lupus familiaris), 515773 (Bos taurus), 714058 (Macaca mulatta)
|
| Target Alternative Names |
0610016L08Rik,2500002N19Rik,B5R,C5BR,CB5R,CYB5R3,Cyb5r3,Cytochrome b5 reductase,DIA1,Dia-1,Dia1,Diaphorase-1,NADH-cytochrome b5 reductase 3,Nadhcb5,RNNADHCB5,WU:Cyb5r3
|
| Uniprot Accession |
Q9DCN2,P00387,P20070,Q0X0E5,P07514
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000008452, ENSMUSG00000018042, ENSG00000100243, ENSCAFG00845014552, ENSBTAG00000016516, ENSMMUG00000010198
|
Pre-made viral vector of CYB5R3 cDNA Clones/ORF Plasmid
CYB5R3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1727 | Pre-made Human CYB5R3/B5R/DIA1 siRNA oligo Duplex | 1727 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25035 | Pre-made Rat Cyb5r3/Dia1/Nadhcb5 siRNA oligo Duplex | 25035 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo109754 | Pre-made Mouse Cyb5r3/B5R/Dia1 siRNA oligo Duplex | 109754 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo714058 | Pre-made Cynomolgus/Rhesus macaque CYB5R3 siRNA oligo Duplex | 714058 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101091382 | Pre-made Cat/Feline CYB5R3 siRNA oligo Duplex | 101091382 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo474479 | Pre-made Dog/Canine CYB5R3/C5BR/CB5R siRNA oligo Duplex | 474479 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo515773 | Pre-made Bovines/Cattle CYB5R3 siRNA oligo Duplex | 515773 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100071050 | Pre-made Equine/Horse CYB5R3 siRNA oligo Duplex | 100071050 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CYB5R3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP6204-Ab | Human | Anti-Human CYB5R3 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP6204-Ab | Rat | Anti-Rat CYB5R3 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP6204-Ab | Mouse | Anti-Mouse CYB5R3 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP6204-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CYB5R3 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP6204-Ab | Cat/Feline | Anti-Cat/Feline CYB5R3 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP6204-Ab | Dog/Canine | Anti-Dog/Canine CYB5R3 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP6204-Ab | Bovines/Cattle | Anti-Bovines/Cattle CYB5R3 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP6204-Ab | Equine/Horse | Anti-Equine/Horse CYB5R3 monoclonal antibody | mab | | Detail |
CYB5R3 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP6204-Ag | Human | Human CYB5R3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP6204-Ag | Rat | Rat CYB5R3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP6204-Ag | Mouse | Mouse CYB5R3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP6204-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CYB5R3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP6204-Ag | Cat/Feline | Cat/Feline CYB5R3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP6204-Ag | Dog/Canine | Dog/Canine CYB5R3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP6204-Ag | Bovines/Cattle | Bovines/Cattle CYB5R3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP6204-Ag | Equine/Horse | Equine/Horse CYB5R3 recombinant protein | Mammalian cell | Detail |