Recombinant multi-species USP18 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine USP18 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene belongs to the ubiquitin-specific proteases (UBP) family of enzymes that cleave ubiquitin from ubiquitinated protein substrates. It is highly expressed in liver and thymus, and is localized to the nucleus. This protein efficiently cleaves only ISG15 (a ubiquitin-like protein) fusions, and deletion of this gene in mice results in a massive increase of ISG15 conjugates in tissues, indicating that this protein is a major ISG15-specific protease. Mice lacking this gene are also hypersensitive to interferon, suggesting a function of this protein in downregulating interferon responses, independent of its isopeptidase activity towards ISG15. [provided by RefSeq, Sep 2011]
The Alternative Names of target: 1110058H21Rik,43 kDa ISG15-specific protease (hUBP43),ISG15-specific-processing protease,ISG43,PTORCH2,UBP43,USP18,Ubl carboxyl-terminal hydrolase 18,Ubl thioesterase 18,Ubp15,Usp18,bubp43

Target products collectionGo to USP18 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP4090-Ag-1/ GM-Tg-hg-IP4090-Ag-2 Human USP18 protein Human
GM-Tg-rg-IP4090-Ag-1/ GM-Tg-rg-IP4090-Ag-2 Rat USP18 protein Rat
GM-Tg-mg-IP4090-Ag-1/ GM-Tg-mg-IP4090-Ag-2 Mouse USP18 protein Mouse
GM-Tg-cynog-IP4090-Ag-1/ GM-Tg-cynog-IP4090-Ag-2 Cynomolgus/Rhesus macaque USP18 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP4090-Ag-1/ GM-Tg-felg-IP4090-Ag-2 Feline USP18 protein Feline
GM-Tg-cang-IP4090-Ag-1/ GM-Tg-cang-IP4090-Ag-2 Canine USP18 protein Canine
GM-Tg-bovg-IP4090-Ag-1/ GM-Tg-bovg-IP4090-Ag-2 Bovine USP18 protein Bovine
GM-Tg-equg-IP4090-Ag-1/ GM-Tg-equg-IP4090-Ag-2 Equine USP18 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP4090-Ag-1/ GM-Tg-hg-IP4090-Ag-2; GM-Tg-rg-IP4090-Ag-1/ GM-Tg-rg-IP4090-Ag-2;
GM-Tg-mg-IP4090-Ag-1/ GM-Tg-mg-IP4090-Ag-2; GM-Tg-cynog-IP4090-Ag-1/ GM-Tg-cynog-IP4090-Ag-2;
GM-Tg-felg-IP4090-Ag-1/ GM-Tg-felg-IP4090-Ag-2; GM-Tg-cang-IP4090-Ag-1/ GM-Tg-cang-IP4090-Ag-2;
GM-Tg-bovg-IP4090-Ag-1/ GM-Tg-bovg-IP4090-Ag-2; GM-Tg-equg-IP4090-Ag-1/ GM-Tg-equg-IP4090-Ag-2
Products Name USP18 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name USP18
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine USP18 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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