USP18 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore USP18 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
The protein encoded by this gene belongs to the ubiquitin-specific proteases (UBP) family of enzymes that cleave ubiquitin from ubiquitinated protein substrates. It is highly expressed in liver and thymus, and is localized to the nucleus. This protein efficiently cleaves only ISG15 (a ubiquitin-like protein) fusions, and deletion of this gene in mice results in a massive increase of ISG15 conjugates in tissues, indicating that this protein is a major ISG15-specific protease. Mice lacking this gene are also hypersensitive to interferon, suggesting a function of this protein in downregulating interferon responses, independent of its isopeptidase activity towards ISG15. [provided by RefSeq, Sep 2011]

Target ID	GM-IP4090
Target Name	USP18
Gene Group ldentifer （Target Gene ID in Homo species)	11274
Gene ID	100054488 (Equus caballus), 101093867 (Felis catus), 11274 (Homo sapiens), 24110 (Mus musculus) 312688 (Rattus norvegicus), 486763 (Canis lupus familiaris), 515202 (Bos taurus), 718792 (Macaca mulatta)
Target Alternative Names	1110058H21Rik,43 kDa ISG15-specific protease (hUBP43),ISG15-specific-processing protease,ISG43,PTORCH2,UBP43,USP18,Ubl carboxyl-terminal hydrolase 18,Ubl thioesterase 18,Ubp15,Usp18,bubp43
Uniprot Accession	Q9UMW8,Q9WTV6
Protein Sub-location	Introcelluar Protein
Category	Life Science Target
Gene Ensembl	ENSECAG00000000284, ENSG00000184979, ENSMUSG00000030107, ENSCAFG00845030962, ENSBTAG00000016661, ENSMMUG00000003272

Pre-made viral vector of USP18 cDNA Clones/ORF Plasmid

Cat No.	Product Name	NMID	GeneID	Species	Type	Marker	Fusion Tag	Promoter	Detail
pGMLP004277	Human USP18/ISG43/PTORCH2 Lentivirus plasmid	NM_017414	11274	Human	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
pGMLV002385	Human USP18/ISG43/PTORCH2 Lentivirus plasmid	NM_017414.4	11274	Human	Lentivirus plasmid	ZsGreen	MYC (C-Terminal)	CMV	Detail
pGMPC000233	Human USP18/ISG43/PTORCH2 Mammalian (Non-Viral Vector) plasmid	NM_017414	11274	Human	Mammalian (Non-Viral Vector) plasmid	EGFP	Null	EF1	Detail
pGMPC001517	Human USP18/ISG43/PTORCH2 Mammalian (Non-Viral Vector) plasmid	NM_017414	11274	Human	Mammalian (Non-Viral Vector) plasmid	EGFP	3xflag (C-Terminal)	EF1	Detail
vGMLP004277	Human USP18/ISG43/PTORCH2 Lentivirus particle	NM_017414	11274	Human	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMLV002385	Human USP18/ISG43/PTORCH2 Lentivirus particle	NM_017414.4	11274	Human	Lentivirus particle	ZsGreen	MYC (C-Terminal)	CMV	Detail
pGMLV001004	Mouse Usp18/1110058H21Rik/AW047653 Lentivirus plasmid	NM_011909	24110	Mouse	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
pGMLV002370	Mouse Usp18/1110058H21Rik/Ubp15 Lentivirus plasmid	NM_011909	24110	Mouse	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
pGMAAV001683	Mouse Usp18/1110058H21Rik/Ubp15 Adeno-associate virus(AAV) plasmid	NM_011909	24110	Mouse	Adeno-associate virus(AAV) plasmid	Null	3xflag (C-Terminal)	CTNT	Detail
pGMLPm003399	Mouse Usp18/1110058H21Rik/AW047653 Lentivirus plasmid	NM_011909	24110	Mouse	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMLV001004	Mouse Usp18/1110058H21Rik/AW047653 Lentivirus particle	NM_011909	24110	Mouse	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMLV002370	Mouse Usp18/1110058H21Rik/Ubp15 Lentivirus particle	NM_011909	24110	Mouse	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMAAV001683	Mouse Usp18/1110058H21Rik/Ubp15 Adeno-associate virus(AAV) particle	NM_011909	24110	Mouse	Adeno-associate virus(AAV) particle	Null	3xflag (C-Terminal)	CTNT	Detail
vGMLPm003399	Mouse Usp18/1110058H21Rik/AW047653 Lentivirus particle	NM_011909	24110	Mouse	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail

USP18 siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.	Product Name	GeneID	Species	Grade	Detail
pGMoligo11274	Pre-made Human USP18/ISG43/UBP43 siRNA oligo Duplex	11274	Human	In-vitro grade; in-vivo grade	Detail
pGMoligo312688	Pre-made Rat Usp18 siRNA oligo Duplex	312688	Rat	In-vitro grade; in-vivo grade	Detail
pGMoligo24110	Pre-made Mouse Usp18/UBP43/Ubp15 siRNA oligo Duplex	24110	Mouse	In-vitro grade; in-vivo grade	Detail
pGMoligo718792	Pre-made Cynomolgus/Rhesus macaque USP18 siRNA oligo Duplex	718792	Cynomolgus/Rhesus macaque	In-vitro grade; in-vivo grade	Detail
pGMoligo101093867	Pre-made Cat/Feline USP18 siRNA oligo Duplex	101093867	Cat/Feline	In-vitro grade; in-vivo grade	Detail
pGMoligo486763	Pre-made Dog/Canine USP18 siRNA oligo Duplex	486763	Dog/Canine	In-vitro grade; in-vivo grade	Detail
pGMoligo515202	Pre-made Bovines/Cattle USP18/bubp43 siRNA oligo Duplex	515202	Bovines/Cattle	In-vitro grade; in-vivo grade	Detail
pGMoligo100054488	Pre-made Equine/Horse USP18 siRNA oligo Duplex	100054488	Equine/Horse	In-vitro grade; in-vivo grade	Detail

USP18 antibody/GMab

Cat No.	Species	Antibody Name	Format	Detail
GM-Tg-hg-IP4090-Ab	Human	Anti-Human USP18 monoclonal antibody	mab	Detail
GM-Tg-rg-IP4090-Ab	Rat	Anti-Rat USP18 monoclonal antibody	mab	Detail
GM-Tg-mg-IP4090-Ab	Mouse	Anti-Mouse USP18 monoclonal antibody	mab	Detail
GM-Tg-cynog-IP4090-Ab	Cynomolgus/Rhesus macaque	Anti-Cynomolgus/Rhesus macaque USP18 monoclonal antibody	mab	Detail
GM-Tg-felg-IP4090-Ab	Cat/Feline	Anti-Cat/Feline USP18 monoclonal antibody	mab	Detail
GM-Tg-cang-IP4090-Ab	Dog/Canine	Anti-Dog/Canine USP18 monoclonal antibody	mab	Detail
GM-Tg-bovg-IP4090-Ab	Bovines/Cattle	Anti-Bovines/Cattle USP18 monoclonal antibody	mab	Detail
GM-Tg-equg-IP4090-Ab	Equine/Horse	Anti-Equine/Horse USP18 monoclonal antibody	mab	Detail

USP18 recombinant protein

Cat No.	Species	Antigen Name	Expression Platform	Detail
GM-Tg-hg-IP4090-Ag	Human	Human USP18 recombinant protein	Mammalian cell	Detail
GM-Tg-rg-IP4090-Ag	Rat	Rat USP18 recombinant protein	Mammalian cell	Detail
GM-Tg-mg-IP4090-Ag	Mouse	Mouse USP18 recombinant protein	Mammalian cell	Detail
GM-Tg-cynog-IP4090-Ag	Cynomolgus/Rhesus macaque	Cynomolgus/Rhesus macaque USP18 recombinant protein	Mammalian cell	Detail
GM-Tg-felg-IP4090-Ag	Cat/Feline	Cat/Feline USP18 recombinant protein	Mammalian cell	Detail
GM-Tg-cang-IP4090-Ag	Dog/Canine	Dog/Canine USP18 recombinant protein	Mammalian cell	Detail
GM-Tg-bovg-IP4090-Ag	Bovines/Cattle	Bovines/Cattle USP18 recombinant protein	Mammalian cell	Detail
GM-Tg-equg-IP4090-Ag	Equine/Horse	Equine/Horse USP18 recombinant protein	Mammalian cell	Detail