Recombinant multi-species PADI2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PADI2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes. [provided by RefSeq, Jul 2008]
The Alternative Names of target: PAD-H19,PAD2,PADI2,PDI2,Padi2,Pdi,Pdi2,Peptidylarginine deiminase II,Protein-arginine deiminase type II,Protein-arginine deiminase type-2,mKIAA0994

Target products collectionGo to PADI2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP4050-Ag-1/ GM-Tg-hg-IP4050-Ag-2 Human PADI2 protein Human
GM-Tg-rg-IP4050-Ag-1/ GM-Tg-rg-IP4050-Ag-2 Rat PADI2 protein Rat
GM-Tg-mg-IP4050-Ag-1/ GM-Tg-mg-IP4050-Ag-2 Mouse PADI2 protein Mouse
GM-Tg-cynog-IP4050-Ag-1/ GM-Tg-cynog-IP4050-Ag-2 Cynomolgus/Rhesus macaque PADI2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP4050-Ag-1/ GM-Tg-felg-IP4050-Ag-2 Feline PADI2 protein Feline
GM-Tg-cang-IP4050-Ag-1/ GM-Tg-cang-IP4050-Ag-2 Canine PADI2 protein Canine
GM-Tg-bovg-IP4050-Ag-1/ GM-Tg-bovg-IP4050-Ag-2 Bovine PADI2 protein Bovine
GM-Tg-equg-IP4050-Ag-1/ GM-Tg-equg-IP4050-Ag-2 Equine PADI2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP4050-Ag-1/ GM-Tg-hg-IP4050-Ag-2; GM-Tg-rg-IP4050-Ag-1/ GM-Tg-rg-IP4050-Ag-2;
GM-Tg-mg-IP4050-Ag-1/ GM-Tg-mg-IP4050-Ag-2; GM-Tg-cynog-IP4050-Ag-1/ GM-Tg-cynog-IP4050-Ag-2;
GM-Tg-felg-IP4050-Ag-1/ GM-Tg-felg-IP4050-Ag-2; GM-Tg-cang-IP4050-Ag-1/ GM-Tg-cang-IP4050-Ag-2;
GM-Tg-bovg-IP4050-Ag-1/ GM-Tg-bovg-IP4050-Ag-2; GM-Tg-equg-IP4050-Ag-1/ GM-Tg-equg-IP4050-Ag-2
Products Name PADI2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PADI2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PADI2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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