Explore PADI2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes. [provided by RefSeq, Jul 2008]
| Target ID |
GM-IP4050
|
| Target Name |
PADI2
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
11240
|
| Gene ID |
100050025 (Equus caballus), 101085301 (Felis catus), 11240 (Homo sapiens), 18600 (Mus musculus) 29511 (Rattus norvegicus), 487414 (Canis lupus familiaris), 617851 (Bos taurus), 711044 (Macaca mulatta)
|
| Target Alternative Names |
PAD-H19,PAD2,PADI2,PDI2,Padi2,Pdi,Pdi2,Peptidylarginine deiminase II,Protein-arginine deiminase type II,Protein-arginine deiminase type-2,mKIAA0994
|
| Uniprot Accession |
Q9Y2J8,Q08642,P20717
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000021856, ENSG00000117115, ENSMUSG00000028927, ENSCAFG00845004203, ENSBTAG00000003403, ENSMMUG00000001616
|
Pre-made viral vector of PADI2 cDNA Clones/ORF Plasmid
PADI2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo11240 | Pre-made Human PADI2/PAD2/PDI2 siRNA oligo Duplex | 11240 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29511 | Pre-made Rat Padi2/Pdi2 siRNA oligo Duplex | 29511 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo18600 | Pre-made Mouse Padi2/Pdi/Pdi2 siRNA oligo Duplex | 18600 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo711044 | Pre-made Cynomolgus/Rhesus macaque PADI2 siRNA oligo Duplex | 711044 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101085301 | Pre-made Cat/Feline PADI2 siRNA oligo Duplex | 101085301 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo487414 | Pre-made Dog/Canine PADI2 siRNA oligo Duplex | 487414 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo617851 | Pre-made Bovines/Cattle PADI2 siRNA oligo Duplex | 617851 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100050025 | Pre-made Equine/Horse PADI2 siRNA oligo Duplex | 100050025 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PADI2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP4050-Ab | Human | Anti-Human PADI2 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP4050-Ab | Rat | Anti-Rat PADI2 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP4050-Ab | Mouse | Anti-Mouse PADI2 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP4050-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PADI2 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP4050-Ab | Cat/Feline | Anti-Cat/Feline PADI2 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP4050-Ab | Dog/Canine | Anti-Dog/Canine PADI2 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP4050-Ab | Bovines/Cattle | Anti-Bovines/Cattle PADI2 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP4050-Ab | Equine/Horse | Anti-Equine/Horse PADI2 monoclonal antibody | mab | | Detail |
PADI2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP4050-Ag | Human | Human PADI2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP4050-Ag | Rat | Rat PADI2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP4050-Ag | Mouse | Mouse PADI2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP4050-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PADI2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP4050-Ag | Cat/Feline | Cat/Feline PADI2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP4050-Ag | Dog/Canine | Dog/Canine PADI2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP4050-Ag | Bovines/Cattle | Bovines/Cattle PADI2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP4050-Ag | Equine/Horse | Equine/Horse PADI2 recombinant protein | Mammalian cell | Detail |