Recombinant multi-species CCM3/PDCD10 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CCM3/PDCD10 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 2410003B13Rik,CCM3,Ccm3,Cerebral cavernous malformations 3 protein,PDCD10,Pdcd10,Programmed cell death protein 10,TF-1 cell apoptosis-related protein 15,TFAR15,Tfa15,Tfar15
Go
to CCM3/PDCD10 products collection
>>
(antibodies,
antigen, VLP, mRNA, ORF viral vector, etc)
Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP4047-Ag-1/ GM-Tg-hg-IP4047-Ag-2 | Human CCM3/PDCD10 protein | Human |
| GM-Tg-rg-IP4047-Ag-1/ GM-Tg-rg-IP4047-Ag-2 | Rat CCM3/PDCD10 protein | Rat |
| GM-Tg-mg-IP4047-Ag-1/ GM-Tg-mg-IP4047-Ag-2 | Mouse CCM3/PDCD10 protein | Mouse |
| GM-Tg-cynog-IP4047-Ag-1/ GM-Tg-cynog-IP4047-Ag-2 | Cynomolgus/Rhesus macaque CCM3/PDCD10 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP4047-Ag-1/ GM-Tg-felg-IP4047-Ag-2 | Feline CCM3/PDCD10 protein | Feline |
| GM-Tg-cang-IP4047-Ag-1/ GM-Tg-cang-IP4047-Ag-2 | Canine CCM3/PDCD10 protein | Canine |
| GM-Tg-bovg-IP4047-Ag-1/ GM-Tg-bovg-IP4047-Ag-2 | Bovine CCM3/PDCD10 protein | Bovine |
| GM-Tg-equg-IP4047-Ag-1/ GM-Tg-equg-IP4047-Ag-2 | Equine CCM3/PDCD10 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP4047-Ag-1/ GM-Tg-hg-IP4047-Ag-2;
GM-Tg-rg-IP4047-Ag-1/ GM-Tg-rg-IP4047-Ag-2;
GM-Tg-mg-IP4047-Ag-1/ GM-Tg-mg-IP4047-Ag-2; GM-Tg-cynog-IP4047-Ag-1/ GM-Tg-cynog-IP4047-Ag-2; GM-Tg-felg-IP4047-Ag-1/ GM-Tg-felg-IP4047-Ag-2; GM-Tg-cang-IP4047-Ag-1/ GM-Tg-cang-IP4047-Ag-2; GM-Tg-bovg-IP4047-Ag-1/ GM-Tg-bovg-IP4047-Ag-2; GM-Tg-equg-IP4047-Ag-1/ GM-Tg-equg-IP4047-Ag-2 |
| Products Name | CCM3/PDCD10 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | CCM3/PDCD10 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CCM3/PDCD10 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.