Recombinant multi-species CCM3/PDCD10 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CCM3/PDCD10 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 2410003B13Rik,CCM3,Ccm3,Cerebral cavernous malformations 3 protein,PDCD10,Pdcd10,Programmed cell death protein 10,TF-1 cell apoptosis-related protein 15,TFAR15,Tfa15,Tfar15

Target products collectionGo to CCM3/PDCD10 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP4047-Ag-1/ GM-Tg-hg-IP4047-Ag-2 Human CCM3/PDCD10 protein Human
GM-Tg-rg-IP4047-Ag-1/ GM-Tg-rg-IP4047-Ag-2 Rat CCM3/PDCD10 protein Rat
GM-Tg-mg-IP4047-Ag-1/ GM-Tg-mg-IP4047-Ag-2 Mouse CCM3/PDCD10 protein Mouse
GM-Tg-cynog-IP4047-Ag-1/ GM-Tg-cynog-IP4047-Ag-2 Cynomolgus/Rhesus macaque CCM3/PDCD10 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP4047-Ag-1/ GM-Tg-felg-IP4047-Ag-2 Feline CCM3/PDCD10 protein Feline
GM-Tg-cang-IP4047-Ag-1/ GM-Tg-cang-IP4047-Ag-2 Canine CCM3/PDCD10 protein Canine
GM-Tg-bovg-IP4047-Ag-1/ GM-Tg-bovg-IP4047-Ag-2 Bovine CCM3/PDCD10 protein Bovine
GM-Tg-equg-IP4047-Ag-1/ GM-Tg-equg-IP4047-Ag-2 Equine CCM3/PDCD10 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP4047-Ag-1/ GM-Tg-hg-IP4047-Ag-2; GM-Tg-rg-IP4047-Ag-1/ GM-Tg-rg-IP4047-Ag-2;
GM-Tg-mg-IP4047-Ag-1/ GM-Tg-mg-IP4047-Ag-2; GM-Tg-cynog-IP4047-Ag-1/ GM-Tg-cynog-IP4047-Ag-2;
GM-Tg-felg-IP4047-Ag-1/ GM-Tg-felg-IP4047-Ag-2; GM-Tg-cang-IP4047-Ag-1/ GM-Tg-cang-IP4047-Ag-2;
GM-Tg-bovg-IP4047-Ag-1/ GM-Tg-bovg-IP4047-Ag-2; GM-Tg-equg-IP4047-Ag-1/ GM-Tg-equg-IP4047-Ag-2
Products Name CCM3/PDCD10 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name CCM3/PDCD10
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CCM3/PDCD10 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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