Explore CCM3/PDCD10 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
| Target ID |
GM-IP4047
|
| Target Name |
CCM3/PDCD10
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
11235
|
| Gene ID |
100057369 (Equus caballus), 101090640 (Felis catus), 11235 (Homo sapiens), 488145 (Canis lupus familiaris) 494345 (Rattus norvegicus), 506411 (Bos taurus), 56426 (Mus musculus), 699597 (Macaca mulatta)
|
| Target Alternative Names |
2410003B13Rik,CCM3,Ccm3,Cerebral cavernous malformations 3 protein,PDCD10,Pdcd10,Programmed cell death protein 10,TF-1 cell apoptosis-related protein 15,TFAR15,Tfa15,Tfar15
|
| Uniprot Accession |
Q9BUL8,Q6NX65,Q8VE70
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Disease |
cancer, Prostate Cancer
|
| Gene Ensembl |
ENSG00000114209, ENSCAFG00845019304, ENSBTAG00000031709, ENSMUSG00000027835, ENSMMUG00000005938
|
Pre-made viral vector of CCM3/PDCD10 cDNA Clones/ORF Plasmid
CCM3/PDCD10 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo11235 | Pre-made Human PDCD10/CCM3/TFAR15 siRNA oligo Duplex | 11235 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo494345 | Pre-made Rat Pdcd10 siRNA oligo Duplex | 494345 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo56426 | Pre-made Mouse Pdcd10/Ccm3/Tfa15 siRNA oligo Duplex | 56426 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo699597 | Pre-made Cynomolgus/Rhesus macaque PDCD10 siRNA oligo Duplex | 699597 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101090640 | Pre-made Cat/Feline PDCD10 siRNA oligo Duplex | 101090640 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo488145 | Pre-made Dog/Canine PDCD10 siRNA oligo Duplex | 488145 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo506411 | Pre-made Bovines/Cattle PDCD10 siRNA oligo Duplex | 506411 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100057369 | Pre-made Equine/Horse PDCD10 siRNA oligo Duplex | 100057369 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CCM3/PDCD10 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP4047-Ab | Human | Anti-Human CCM3/PDCD10 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP4047-Ab | Rat | Anti-Rat CCM3/PDCD10 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP4047-Ab | Mouse | Anti-Mouse CCM3/PDCD10 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP4047-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CCM3/PDCD10 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP4047-Ab | Cat/Feline | Anti-Cat/Feline CCM3/PDCD10 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP4047-Ab | Dog/Canine | Anti-Dog/Canine CCM3/PDCD10 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP4047-Ab | Bovines/Cattle | Anti-Bovines/Cattle CCM3/PDCD10 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP4047-Ab | Equine/Horse | Anti-Equine/Horse CCM3/PDCD10 monoclonal antibody | mab | | Detail |
CCM3/PDCD10 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP4047-Ag | Human | Human CCM3/PDCD10 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP4047-Ag | Rat | Rat CCM3/PDCD10 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP4047-Ag | Mouse | Mouse CCM3/PDCD10 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP4047-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CCM3/PDCD10 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP4047-Ag | Cat/Feline | Cat/Feline CCM3/PDCD10 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP4047-Ag | Dog/Canine | Dog/Canine CCM3/PDCD10 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP4047-Ag | Bovines/Cattle | Bovines/Cattle CCM3/PDCD10 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP4047-Ag | Equine/Horse | Equine/Horse CCM3/PDCD10 recombinant protein | Mammalian cell | Detail |