Recombinant multi-species PRDX3/PRX3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PRDX3/PRX3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a mitochondrial protein with antioxidant function. The protein is similar to the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase, and it can rescue bacterial resistance to alkylhydroperoxide in E. coli that lack the C22 subunit. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologs suggest that these genes consist of a family that is responsible for the regulation of cellular proliferation, differentiation and antioxidant functions. This family member can protect cells from oxidative stress, and it can promote cell survival in prostate cancer. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1, 3, 13 and 22. [provided by RefSeq, Oct 2014]
The Alternative Names of target: AOP-1,AOP1,Antioxidant protein 1 (AOP-1),Aop1,D0Tohi1,Ef2l,HBC189,MER5,MTAP,Mer5,PPPCD,PRDX3,PRO1748,PRX3,Peroxiredoxin III (Prx-III),Peroxiredoxin-3,Prdx3,Protein MER5 homolog,Prx3,SCAR32,SP-22,SP22,TDXM,Thioredoxin-dependent peroxide reductase,Thioredoxin-dependent peroxiredoxin 3,mitochondrial,prx-III

Target products collectionGo to PRDX3/PRX3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP3865-Ag-1/ GM-Tg-hg-IP3865-Ag-2 Human PRDX3/PRX3 protein Human
GM-Tg-rg-IP3865-Ag-1/ GM-Tg-rg-IP3865-Ag-2 Rat PRDX3/PRX3 protein Rat
GM-Tg-mg-IP3865-Ag-1/ GM-Tg-mg-IP3865-Ag-2 Mouse PRDX3/PRX3 protein Mouse
GM-Tg-cynog-IP3865-Ag-1/ GM-Tg-cynog-IP3865-Ag-2 Cynomolgus/Rhesus macaque PRDX3/PRX3 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP3865-Ag-1/ GM-Tg-felg-IP3865-Ag-2 Feline PRDX3/PRX3 protein Feline
GM-Tg-cang-IP3865-Ag-1/ GM-Tg-cang-IP3865-Ag-2 Canine PRDX3/PRX3 protein Canine
GM-Tg-bovg-IP3865-Ag-1/ GM-Tg-bovg-IP3865-Ag-2 Bovine PRDX3/PRX3 protein Bovine
GM-Tg-equg-IP3865-Ag-1/ GM-Tg-equg-IP3865-Ag-2 Equine PRDX3/PRX3 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP3865-Ag-1/ GM-Tg-hg-IP3865-Ag-2; GM-Tg-rg-IP3865-Ag-1/ GM-Tg-rg-IP3865-Ag-2;
GM-Tg-mg-IP3865-Ag-1/ GM-Tg-mg-IP3865-Ag-2; GM-Tg-cynog-IP3865-Ag-1/ GM-Tg-cynog-IP3865-Ag-2;
GM-Tg-felg-IP3865-Ag-1/ GM-Tg-felg-IP3865-Ag-2; GM-Tg-cang-IP3865-Ag-1/ GM-Tg-cang-IP3865-Ag-2;
GM-Tg-bovg-IP3865-Ag-1/ GM-Tg-bovg-IP3865-Ag-2; GM-Tg-equg-IP3865-Ag-1/ GM-Tg-equg-IP3865-Ag-2
Products Name PRDX3/PRX3 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PRDX3/PRX3
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PRDX3/PRX3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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