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Target
sublocation: Introcelluar Protein.
This gene encodes a mitochondrial protein with antioxidant function. The protein is similar to the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase, and it can rescue bacterial resistance to alkylhydroperoxide in E. coli that lack the C22 subunit. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologs suggest that these genes consist of a family that is responsible for the regulation of cellular proliferation, differentiation and antioxidant functions. This family member can protect cells from oxidative stress, and it can promote cell survival in prostate cancer. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1, 3, 13 and 22. [provided by RefSeq, Oct 2014]
| Target ID |
GM-IP3865
|
| Target Name |
PRDX3/PRX3
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
10935
|
| Gene ID |
100058646 (Equus caballus), 101088618 (Felis catus), 10935 (Homo sapiens), 11757 (Mus musculus) 281998 (Bos taurus), 477839 (Canis lupus familiaris), 64371 (Rattus norvegicus), 702882 (Macaca mulatta)
|
| Target Alternative Names |
AOP-1,AOP1,Antioxidant protein 1 (AOP-1),Aop1,D0Tohi1,Ef2l,HBC189,MER5,MTAP,Mer5,PPPCD,PRDX3,PRO1748,PRX3,Peroxiredoxin III (Prx-III),Peroxiredoxin-3,Prdx3,Protein MER5 homolog,Prx3,SCAR32,SP-22,SP22,TDXM,Thioredoxin-dependent peroxide reductase,Thioredoxin-dependent peroxiredoxin 3,mitochondrial,prx-III
|
| Uniprot Accession |
P30048,P20108,P35705,Q9Z0V6
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000017026, ENSG00000165672, ENSMUSG00000024997, ENSBTAG00000008731, ENSCAFG00845016072, ENSMMUG00000008294
|
Pre-made viral vector of PRDX3/PRX3 cDNA Clones/ORF Plasmid
PRDX3/PRX3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo10935 | Pre-made Human PRDX3/AOP1/MER5 siRNA oligo Duplex | 10935 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo64371 | Pre-made Rat Prdx3/Prx3 siRNA oligo Duplex | 64371 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo11757 | Pre-made Mouse Prdx3/Aop1/Ef2l siRNA oligo Duplex | 11757 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo702882 | Pre-made Cynomolgus/Rhesus macaque PRDX3 siRNA oligo Duplex | 702882 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101088618 | Pre-made Cat/Feline PRDX3 siRNA oligo Duplex | 101088618 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo477839 | Pre-made Dog/Canine PRDX3/AOP1 siRNA oligo Duplex | 477839 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281998 | Pre-made Bovines/Cattle PRDX3/MTAP siRNA oligo Duplex | 281998 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100058646 | Pre-made Equine/Horse PRDX3 siRNA oligo Duplex | 100058646 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PRDX3/PRX3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP3865-Ab | Human | Anti-Human PRDX3/PRX3 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP3865-Ab | Rat | Anti-Rat PRDX3/PRX3 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP3865-Ab | Mouse | Anti-Mouse PRDX3/PRX3 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP3865-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PRDX3/PRX3 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP3865-Ab | Cat/Feline | Anti-Cat/Feline PRDX3/PRX3 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP3865-Ab | Dog/Canine | Anti-Dog/Canine PRDX3/PRX3 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP3865-Ab | Bovines/Cattle | Anti-Bovines/Cattle PRDX3/PRX3 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP3865-Ab | Equine/Horse | Anti-Equine/Horse PRDX3/PRX3 monoclonal antibody | mab | | Detail |
PRDX3/PRX3 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP3865-Ag | Human | Human PRDX3/PRX3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP3865-Ag | Rat | Rat PRDX3/PRX3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP3865-Ag | Mouse | Mouse PRDX3/PRX3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP3865-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PRDX3/PRX3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP3865-Ag | Cat/Feline | Cat/Feline PRDX3/PRX3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP3865-Ag | Dog/Canine | Dog/Canine PRDX3/PRX3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP3865-Ag | Bovines/Cattle | Bovines/Cattle PRDX3/PRX3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP3865-Ag | Equine/Horse | Equine/Horse PRDX3/PRX3 recombinant protein | Mammalian cell | Detail |