Recombinant multi-species PGC1a/PPARGC1A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PGC1a/PPARGC1A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. [provided by RefSeq, Jul 2008]
The Alternative Names of target: A830037N07Rik,Gm11133,LEM6,LRPGC1,Ligand effect modulator 6,PGC-1,PGC-1(alpha),PGC-1-alpha,PGC-1alpha,PGC-1v,PGC1,PGC1A,PGC1a,PGCvf,PGCvf-1,PGCvf1,PPAR-gamma coactivator 1-alpha,PPARGC-1-alpha,PPARGC-1A,PPARGC1,PPARGC1A,Peroxisome proliferator-activated receptor gamma coactivator 1-alpha,Pgc-1alpha,Pgc1,Pgco1,Ppargc1,Ppargc1a

Target products collectionGo to PGC1a/PPARGC1A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP3846-Ag-1/ GM-Tg-hg-IP3846-Ag-2 Human PGC1a/PPARGC1A protein Human
GM-Tg-rg-IP3846-Ag-1/ GM-Tg-rg-IP3846-Ag-2 Rat PGC1a/PPARGC1A protein Rat
GM-Tg-mg-IP3846-Ag-1/ GM-Tg-mg-IP3846-Ag-2 Mouse PGC1a/PPARGC1A protein Mouse
GM-Tg-cynog-IP3846-Ag-1/ GM-Tg-cynog-IP3846-Ag-2 Cynomolgus/Rhesus macaque PGC1a/PPARGC1A protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP3846-Ag-1/ GM-Tg-felg-IP3846-Ag-2 Feline PGC1a/PPARGC1A protein Feline
GM-Tg-cang-IP3846-Ag-1/ GM-Tg-cang-IP3846-Ag-2 Canine PGC1a/PPARGC1A protein Canine
GM-Tg-bovg-IP3846-Ag-1/ GM-Tg-bovg-IP3846-Ag-2 Bovine PGC1a/PPARGC1A protein Bovine
GM-Tg-equg-IP3846-Ag-1/ GM-Tg-equg-IP3846-Ag-2 Equine PGC1a/PPARGC1A protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP3846-Ag-1/ GM-Tg-hg-IP3846-Ag-2; GM-Tg-rg-IP3846-Ag-1/ GM-Tg-rg-IP3846-Ag-2;
GM-Tg-mg-IP3846-Ag-1/ GM-Tg-mg-IP3846-Ag-2; GM-Tg-cynog-IP3846-Ag-1/ GM-Tg-cynog-IP3846-Ag-2;
GM-Tg-felg-IP3846-Ag-1/ GM-Tg-felg-IP3846-Ag-2; GM-Tg-cang-IP3846-Ag-1/ GM-Tg-cang-IP3846-Ag-2;
GM-Tg-bovg-IP3846-Ag-1/ GM-Tg-bovg-IP3846-Ag-2; GM-Tg-equg-IP3846-Ag-1/ GM-Tg-equg-IP3846-Ag-2
Products Name PGC1a/PPARGC1A protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PGC1a/PPARGC1A
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PGC1a/PPARGC1A protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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