Recombinant multi-species DLC1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DLC1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a GTPase-activating protein (GAP) that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene.[provided by RefSeq, Apr 2010]
The Alternative Names of target: A730069N07Rik,ARHGAP7,Arhgap7,DLC-1,DLC1,Deleted in liver cancer 1 protein (DLC-1),Dlc-1,Dlc1,HP,HP protein,Rho GTPase-activating protein 7,Rho-type GTPase-activating protein 7,RhoGAP,STARD12,START domain-containing protein 12 (StARD12),StAR-related lipid transfer protein 12,StARD12,dlc-1,p122-RhoGAP

Target products collectionGo to DLC1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP3500-Ag-1/ GM-Tg-hg-IP3500-Ag-2 Human DLC1 protein Human
GM-Tg-rg-IP3500-Ag-1/ GM-Tg-rg-IP3500-Ag-2 Rat DLC1 protein Rat
GM-Tg-mg-IP3500-Ag-1/ GM-Tg-mg-IP3500-Ag-2 Mouse DLC1 protein Mouse
GM-Tg-cynog-IP3500-Ag-1/ GM-Tg-cynog-IP3500-Ag-2 Cynomolgus/Rhesus macaque DLC1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP3500-Ag-1/ GM-Tg-felg-IP3500-Ag-2 Feline DLC1 protein Feline
GM-Tg-cang-IP3500-Ag-1/ GM-Tg-cang-IP3500-Ag-2 Canine DLC1 protein Canine
GM-Tg-bovg-IP3500-Ag-1/ GM-Tg-bovg-IP3500-Ag-2 Bovine DLC1 protein Bovine
GM-Tg-equg-IP3500-Ag-1/ GM-Tg-equg-IP3500-Ag-2 Equine DLC1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP3500-Ag-1/ GM-Tg-hg-IP3500-Ag-2; GM-Tg-rg-IP3500-Ag-1/ GM-Tg-rg-IP3500-Ag-2;
GM-Tg-mg-IP3500-Ag-1/ GM-Tg-mg-IP3500-Ag-2; GM-Tg-cynog-IP3500-Ag-1/ GM-Tg-cynog-IP3500-Ag-2;
GM-Tg-felg-IP3500-Ag-1/ GM-Tg-felg-IP3500-Ag-2; GM-Tg-cang-IP3500-Ag-1/ GM-Tg-cang-IP3500-Ag-2;
GM-Tg-bovg-IP3500-Ag-1/ GM-Tg-bovg-IP3500-Ag-2; GM-Tg-equg-IP3500-Ag-1/ GM-Tg-equg-IP3500-Ag-2
Products Name DLC1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name DLC1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DLC1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.