Explore DLC1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
This gene encodes a GTPase-activating protein (GAP) that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene.[provided by RefSeq, Apr 2010]
| Target ID |
GM-IP3500
|
| Target Name |
DLC1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
10395
|
| Gene ID |
100052317 (Equus caballus), 101086801 (Felis catus), 10395 (Homo sapiens), 475607 (Canis lupus familiaris)
50768 (Mus musculus), 511433 (Bos taurus), 58834 (Rattus norvegicus), 700630 (Macaca mulatta)
|
| Target Alternative Names |
A730069N07Rik,ARHGAP7,Arhgap7,DLC-1,DLC1,Deleted in liver cancer 1 protein (DLC-1),Dlc-1,Dlc1,HP,HP protein,Rho GTPase-activating protein 7,Rho-type GTPase-activating protein 7,RhoGAP,STARD12,START domain-containing protein 12 (StARD12),StAR-related lipid transfer protein 12,StARD12,dlc-1,p122-RhoGAP
|
| Uniprot Accession |
Q96QB1,B9VTT2,Q9R0Z9,A7E300,Q63744
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000013988, ENSG00000164741, ENSCAFG00845013729, ENSMUSG00000031523, ENSBTAG00000015541, ENSMMUG00000015144
|
DLC1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo10395 | Pre-made Human DLC1/HP/ARHGAP7 siRNA oligo Duplex | 10395 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo58834 | Pre-made Rat Dlc1/RhoGAP/Arhgap7 siRNA oligo Duplex | 58834 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo50768 | Pre-made Mouse Dlc1/HP/dlc-1 siRNA oligo Duplex | 50768 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo700630 | Pre-made Cynomolgus/Rhesus macaque DLC1 siRNA oligo Duplex | 700630 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101086801 | Pre-made Cat/Feline DLC1 siRNA oligo Duplex | 101086801 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo475607 | Pre-made Dog/Canine DLC1/Dlc-1/ARHGAP7 siRNA oligo Duplex | 475607 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo511433 | Pre-made Bovines/Cattle DLC1/DLC-1/StARD12 siRNA oligo Duplex | 511433 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100052317 | Pre-made Equine/Horse DLC1 siRNA oligo Duplex | 100052317 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
DLC1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP3500-Ab | Human | Anti-Human DLC1 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP3500-Ab | Rat | Anti-Rat DLC1 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP3500-Ab | Mouse | Anti-Mouse DLC1 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP3500-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque DLC1 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP3500-Ab | Cat/Feline | Anti-Cat/Feline DLC1 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP3500-Ab | Dog/Canine | Anti-Dog/Canine DLC1 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP3500-Ab | Bovines/Cattle | Anti-Bovines/Cattle DLC1 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP3500-Ab | Equine/Horse | Anti-Equine/Horse DLC1 monoclonal antibody | mab | | Detail |
DLC1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP3500-Ag | Human | Human DLC1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP3500-Ag | Rat | Rat DLC1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP3500-Ag | Mouse | Mouse DLC1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP3500-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque DLC1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP3500-Ag | Cat/Feline | Cat/Feline DLC1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP3500-Ag | Dog/Canine | Dog/Canine DLC1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP3500-Ag | Bovines/Cattle | Bovines/Cattle DLC1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP3500-Ag | Equine/Horse | Equine/Horse DLC1 recombinant protein | Mammalian cell | Detail |
