Recombinant multi-species OPTN protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine OPTN protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 4930441O07Rik,ALS12,E3-14.7K-interacting protein (FIP-2),FIP2,Fip2,GLC1E,HIP7,HYPL,Huntingtin yeast partner L,Huntingtin-interacting protein 7 (HIP-7),Huntingtin-interacting protein L,NEMO-related protein,NRP,OPTN,Optic neuropathy-inducing protein,Optineurin,Optn,TFIIIA-INTP,Transcription factor IIIA-interacting protein (TFIIIA-IntP)

Target products collectionGo to OPTN products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP3298-Ag-1/ GM-Tg-hg-IP3298-Ag-2 Human OPTN protein Human
GM-Tg-rg-IP3298-Ag-1/ GM-Tg-rg-IP3298-Ag-2 Rat OPTN protein Rat
GM-Tg-mg-IP3298-Ag-1/ GM-Tg-mg-IP3298-Ag-2 Mouse OPTN protein Mouse
GM-Tg-cynog-IP3298-Ag-1/ GM-Tg-cynog-IP3298-Ag-2 Cynomolgus/Rhesus macaque OPTN protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP3298-Ag-1/ GM-Tg-felg-IP3298-Ag-2 Feline OPTN protein Feline
GM-Tg-cang-IP3298-Ag-1/ GM-Tg-cang-IP3298-Ag-2 Canine OPTN protein Canine
GM-Tg-bovg-IP3298-Ag-1/ GM-Tg-bovg-IP3298-Ag-2 Bovine OPTN protein Bovine
GM-Tg-equg-IP3298-Ag-1/ GM-Tg-equg-IP3298-Ag-2 Equine OPTN protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP3298-Ag-1/ GM-Tg-hg-IP3298-Ag-2; GM-Tg-rg-IP3298-Ag-1/ GM-Tg-rg-IP3298-Ag-2;
GM-Tg-mg-IP3298-Ag-1/ GM-Tg-mg-IP3298-Ag-2; GM-Tg-cynog-IP3298-Ag-1/ GM-Tg-cynog-IP3298-Ag-2;
GM-Tg-felg-IP3298-Ag-1/ GM-Tg-felg-IP3298-Ag-2; GM-Tg-cang-IP3298-Ag-1/ GM-Tg-cang-IP3298-Ag-2;
GM-Tg-bovg-IP3298-Ag-1/ GM-Tg-bovg-IP3298-Ag-2; GM-Tg-equg-IP3298-Ag-1/ GM-Tg-equg-IP3298-Ag-2
Products Name OPTN protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name OPTN
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine OPTN protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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