Recombinant multi-species BCL2L11/BIM/Bim protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BCL2L11/BIM/Bim protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Jun 2013]
The Alternative Names of target: 1500006F24Rik,BAM,BCL2L11,BIM,BOD,Bcl-2-like protein 11,Bcl2-L-11,Bcl2-interacting mediator of cell death,Bcl2l11,Bim,BimL,Bod,bcl2-L-11

Target products collectionGo to BCL2L11/BIM/Bim products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP3067-Ag-1/ GM-Tg-hg-IP3067-Ag-2 Human BCL2L11/BIM/Bim protein Human
GM-Tg-rg-IP3067-Ag-1/ GM-Tg-rg-IP3067-Ag-2 Rat BCL2L11/BIM/Bim protein Rat
GM-Tg-mg-IP3067-Ag-1/ GM-Tg-mg-IP3067-Ag-2 Mouse BCL2L11/BIM/Bim protein Mouse
GM-Tg-cynog-IP3067-Ag-1/ GM-Tg-cynog-IP3067-Ag-2 Cynomolgus/Rhesus macaque BCL2L11/BIM/Bim protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP3067-Ag-1/ GM-Tg-felg-IP3067-Ag-2 Feline BCL2L11/BIM/Bim protein Feline
GM-Tg-cang-IP3067-Ag-1/ GM-Tg-cang-IP3067-Ag-2 Canine BCL2L11/BIM/Bim protein Canine
GM-Tg-bovg-IP3067-Ag-1/ GM-Tg-bovg-IP3067-Ag-2 Bovine BCL2L11/BIM/Bim protein Bovine
GM-Tg-equg-IP3067-Ag-1/ GM-Tg-equg-IP3067-Ag-2 Equine BCL2L11/BIM/Bim protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP3067-Ag-1/ GM-Tg-hg-IP3067-Ag-2; GM-Tg-rg-IP3067-Ag-1/ GM-Tg-rg-IP3067-Ag-2;
GM-Tg-mg-IP3067-Ag-1/ GM-Tg-mg-IP3067-Ag-2; GM-Tg-cynog-IP3067-Ag-1/ GM-Tg-cynog-IP3067-Ag-2;
GM-Tg-felg-IP3067-Ag-1/ GM-Tg-felg-IP3067-Ag-2; GM-Tg-cang-IP3067-Ag-1/ GM-Tg-cang-IP3067-Ag-2;
GM-Tg-bovg-IP3067-Ag-1/ GM-Tg-bovg-IP3067-Ag-2; GM-Tg-equg-IP3067-Ag-1/ GM-Tg-equg-IP3067-Ag-2
Products Name BCL2L11/BIM/Bim protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name BCL2L11/BIM/Bim
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BCL2L11/BIM/Bim protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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