Recombinant multi-species TCEB1/ELOC protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TCEB1/ELOC protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes the protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been identified. [provided by RefSeq, Mar 2011]
The Alternative Names of target: 2610043E24Rik,2610301I15Rik,ELOC,EloC,Eloc,Elongin 15 kDa subunit,Elongin-C,RNA polymerase II transcription factor SIII subunit C,SIII,SIII p15,TCEB1,Tceb1,Transcription elongation factor B polypeptide 1
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP2473-Ag-1/ GM-Tg-hg-IP2473-Ag-2 | Human TCEB1/ELOC protein | Human |
| GM-Tg-rg-IP2473-Ag-1/ GM-Tg-rg-IP2473-Ag-2 | Rat TCEB1/ELOC protein | Rat |
| GM-Tg-mg-IP2473-Ag-1/ GM-Tg-mg-IP2473-Ag-2 | Mouse TCEB1/ELOC protein | Mouse |
| GM-Tg-cynog-IP2473-Ag-1/ GM-Tg-cynog-IP2473-Ag-2 | Cynomolgus/Rhesus macaque TCEB1/ELOC protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP2473-Ag-1/ GM-Tg-felg-IP2473-Ag-2 | Feline TCEB1/ELOC protein | Feline |
| GM-Tg-cang-IP2473-Ag-1/ GM-Tg-cang-IP2473-Ag-2 | Canine TCEB1/ELOC protein | Canine |
| GM-Tg-bovg-IP2473-Ag-1/ GM-Tg-bovg-IP2473-Ag-2 | Bovine TCEB1/ELOC protein | Bovine |
| GM-Tg-equg-IP2473-Ag-1/ GM-Tg-equg-IP2473-Ag-2 | Equine TCEB1/ELOC protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP2473-Ag-1/ GM-Tg-hg-IP2473-Ag-2;
GM-Tg-rg-IP2473-Ag-1/ GM-Tg-rg-IP2473-Ag-2;
GM-Tg-mg-IP2473-Ag-1/ GM-Tg-mg-IP2473-Ag-2; GM-Tg-cynog-IP2473-Ag-1/ GM-Tg-cynog-IP2473-Ag-2; GM-Tg-felg-IP2473-Ag-1/ GM-Tg-felg-IP2473-Ag-2; GM-Tg-cang-IP2473-Ag-1/ GM-Tg-cang-IP2473-Ag-2; GM-Tg-bovg-IP2473-Ag-1/ GM-Tg-bovg-IP2473-Ag-2; GM-Tg-equg-IP2473-Ag-1/ GM-Tg-equg-IP2473-Ag-2 |
| Products Name | TCEB1/ELOC protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | TCEB1/ELOC |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TCEB1/ELOC protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
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myriad domains of biological drug
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innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.