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Target
sublocation: Introcelluar Protein.
This gene encodes the protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been identified. [provided by RefSeq, Mar 2011]
| Target ID |
GM-IP2473
|
| Target Name |
TCEB1/ELOC
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
6921
|
| Gene ID |
100060902 (Equus caballus), 100628309 (Felis catus), 477914 (Canis lupus familiaris), 540859 (Bos taurus) 64525 (Rattus norvegicus), 67923 (Mus musculus), 6921 (Homo sapiens), 698922 (Macaca mulatta)
|
| Target Alternative Names |
2610043E24Rik,2610301I15Rik,ELOC,EloC,Eloc,Elongin 15 kDa subunit,Elongin-C,RNA polymerase II transcription factor SIII subunit C,SIII,SIII p15,TCEB1,Tceb1,Transcription elongation factor B polypeptide 1
|
| Uniprot Accession |
Q2KII4,P83941,P83940,Q15369
|
| Protein Sub-location |
Introcelluar Protein
|
| Disease from KEGG |
HIF-1 signaling pathway, Pathways in cancer, Renal cell carcinoma
|
| Gene Ensembl |
ENSECAG00000000064, ENSCAFG00845028788, ENSBTAG00000050514, ENSMUSG00000079658, ENSG00000154582
|
TCEB1/ELOC siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6921 | Pre-made Human ELOC/SIII/TCEB1 siRNA oligo Duplex | 6921 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo64525 | Pre-made Rat Eloc/Tceb1 siRNA oligo Duplex | 64525 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo67923 | Pre-made Mouse Eloc/Tceb1/2610043E24Rik siRNA oligo Duplex | 67923 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo698922 | Pre-made Cynomolgus/Rhesus macaque ELOC/TCEB1 siRNA oligo Duplex | 698922 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100628309 | Pre-made Cat/Feline ELOC/TCEB1 siRNA oligo Duplex | 100628309 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo477914 | Pre-made Dog/Canine ELOC/TCEB1 siRNA oligo Duplex | 477914 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo540859 | Pre-made Bovines/Cattle ELOC/TCEB1 siRNA oligo Duplex | 540859 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100060902 | Pre-made Equine/Horse ELOC/TCEB1 siRNA oligo Duplex | 100060902 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
TCEB1/ELOC antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP2473-Ab | Human | Anti-Human TCEB1/ELOC monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP2473-Ab | Rat | Anti-Rat TCEB1/ELOC monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP2473-Ab | Mouse | Anti-Mouse TCEB1/ELOC monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP2473-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque TCEB1/ELOC monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP2473-Ab | Cat/Feline | Anti-Cat/Feline TCEB1/ELOC monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP2473-Ab | Dog/Canine | Anti-Dog/Canine TCEB1/ELOC monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP2473-Ab | Bovines/Cattle | Anti-Bovines/Cattle TCEB1/ELOC monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP2473-Ab | Equine/Horse | Anti-Equine/Horse TCEB1/ELOC monoclonal antibody | mab | | Detail |
TCEB1/ELOC recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP2473-Ag | Human | Human TCEB1/ELOC recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP2473-Ag | Rat | Rat TCEB1/ELOC recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP2473-Ag | Mouse | Mouse TCEB1/ELOC recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP2473-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque TCEB1/ELOC recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP2473-Ag | Cat/Feline | Cat/Feline TCEB1/ELOC recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP2473-Ag | Dog/Canine | Dog/Canine TCEB1/ELOC recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP2473-Ag | Bovines/Cattle | Bovines/Cattle TCEB1/ELOC recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP2473-Ag | Equine/Horse | Equine/Horse TCEB1/ELOC recombinant protein | Mammalian cell | Detail |