Recombinant multi-species TMPO/LAP2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TMPO/LAP2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Through alternative splicing, this gene encodes several distinct LEM domain containing protein isoforms. LEM domain proteins include inner nuclear membrane and intranuclear proteins, and are involved in a variety of cellular functions including gene expression, chromatin organization, and replication and cell cycle control. The encoded alpha isoform is broadly diffuse in the nucleus and contains a lamin binding domain, while the beta and gamma isoforms are localized to the nuclear membrane and contain an HDAC3 interaction domain. The distinct isoforms may compete with each other when acting to chaperone other proteins and regulate transcription. [provided by RefSeq, Aug 2019]
The Alternative Names of target: 5630400D24Rik,CMD1T,LAP2,LAP2beta,LEMD4,PRO0868,TMPO,TP,Tmpo

Target products collectionGo to TMPO/LAP2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP2143-Ag-1/ GM-Tg-hg-IP2143-Ag-2 Human TMPO/LAP2 protein Human
GM-Tg-rg-IP2143-Ag-1/ GM-Tg-rg-IP2143-Ag-2 Rat TMPO/LAP2 protein Rat
GM-Tg-mg-IP2143-Ag-1/ GM-Tg-mg-IP2143-Ag-2 Mouse TMPO/LAP2 protein Mouse
GM-Tg-cynog-IP2143-Ag-1/ GM-Tg-cynog-IP2143-Ag-2 Cynomolgus/Rhesus macaque TMPO/LAP2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP2143-Ag-1/ GM-Tg-felg-IP2143-Ag-2 Feline TMPO/LAP2 protein Feline
GM-Tg-cang-IP2143-Ag-1/ GM-Tg-cang-IP2143-Ag-2 Canine TMPO/LAP2 protein Canine
GM-Tg-bovg-IP2143-Ag-1/ GM-Tg-bovg-IP2143-Ag-2 Bovine TMPO/LAP2 protein Bovine
GM-Tg-equg-IP2143-Ag-1/ GM-Tg-equg-IP2143-Ag-2 Equine TMPO/LAP2 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP2143-Ag-1/ GM-Tg-hg-IP2143-Ag-2; GM-Tg-rg-IP2143-Ag-1/ GM-Tg-rg-IP2143-Ag-2;
GM-Tg-mg-IP2143-Ag-1/ GM-Tg-mg-IP2143-Ag-2; GM-Tg-cynog-IP2143-Ag-1/ GM-Tg-cynog-IP2143-Ag-2;
GM-Tg-felg-IP2143-Ag-1/ GM-Tg-felg-IP2143-Ag-2; GM-Tg-cang-IP2143-Ag-1/ GM-Tg-cang-IP2143-Ag-2;
GM-Tg-bovg-IP2143-Ag-1/ GM-Tg-bovg-IP2143-Ag-2; GM-Tg-equg-IP2143-Ag-1/ GM-Tg-equg-IP2143-Ag-2
Products Name TMPO/LAP2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name TMPO/LAP2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TMPO/LAP2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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