Explore TMPO/LAP2 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
Through alternative splicing, this gene encodes several distinct LEM domain containing protein isoforms. LEM domain proteins include inner nuclear membrane and intranuclear proteins, and are involved in a variety of cellular functions including gene expression, chromatin organization, and replication and cell cycle control. The encoded alpha isoform is broadly diffuse in the nucleus and contains a lamin binding domain, while the beta and gamma isoforms are localized to the nuclear membrane and contain an HDAC3 interaction domain. The distinct isoforms may compete with each other when acting to chaperone other proteins and regulate transcription. [provided by RefSeq, Aug 2019]
| Target ID |
GM-IP2143
|
| Target Name |
TMPO/LAP2
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
7112
|
| Gene ID |
100066155 (Equus caballus), 101093283 (Felis catus), 21917 (Mus musculus), 25359 (Rattus norvegicus) 482618 (Canis lupus familiaris), 510267 (Bos taurus), 693387 (Macaca mulatta), 7112 (Homo sapiens)
|
| Target Alternative Names |
5630400D24Rik,CMD1T,LAP2,LAP2beta,LEMD4,PRO0868,TMPO,TP,Tmpo
|
| Uniprot Accession |
Q61029,Q61033,Q62733,P42166,P42167
|
| Protein Sub-location |
Introcelluar Protein
|
| Gene Ensembl |
ENSECAG00000023461, ENSMUSG00000019961, ENSCAFG00845026620, ENSBTAG00000004240, ENSMMUG00000023719, ENSG00000120802
|
Pre-made viral vector of TMPO/LAP2 cDNA Clones/ORF Plasmid
TMPO/LAP2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo7112 | Pre-made Human TMPO/TP/LAP2 siRNA oligo Duplex | 7112 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25359 | Pre-made Rat Tmpo/LAP2 siRNA oligo Duplex | 25359 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo21917 | Pre-made Mouse Tmpo/TP/LAP2 siRNA oligo Duplex | 21917 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo693387 | Pre-made Cynomolgus/Rhesus macaque TMPO siRNA oligo Duplex | 693387 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101093283 | Pre-made Cat/Feline TMPO siRNA oligo Duplex | 101093283 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo482618 | Pre-made Dog/Canine TMPO siRNA oligo Duplex | 482618 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo510267 | Pre-made Bovines/Cattle TMPO/LAP2beta siRNA oligo Duplex | 510267 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100066155 | Pre-made Equine/Horse TMPO siRNA oligo Duplex | 100066155 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
TMPO/LAP2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP2143-Ab | Human | Anti-Human TMPO/LAP2 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP2143-Ab | Rat | Anti-Rat TMPO/LAP2 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP2143-Ab | Mouse | Anti-Mouse TMPO/LAP2 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP2143-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque TMPO/LAP2 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP2143-Ab | Cat/Feline | Anti-Cat/Feline TMPO/LAP2 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP2143-Ab | Dog/Canine | Anti-Dog/Canine TMPO/LAP2 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP2143-Ab | Bovines/Cattle | Anti-Bovines/Cattle TMPO/LAP2 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP2143-Ab | Equine/Horse | Anti-Equine/Horse TMPO/LAP2 monoclonal antibody | mab | | Detail |
TMPO/LAP2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP2143-Ag | Human | Human TMPO/LAP2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP2143-Ag | Rat | Rat TMPO/LAP2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP2143-Ag | Mouse | Mouse TMPO/LAP2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP2143-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque TMPO/LAP2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP2143-Ag | Cat/Feline | Cat/Feline TMPO/LAP2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP2143-Ag | Dog/Canine | Dog/Canine TMPO/LAP2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP2143-Ag | Bovines/Cattle | Bovines/Cattle TMPO/LAP2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP2143-Ag | Equine/Horse | Equine/Horse TMPO/LAP2 recombinant protein | Mammalian cell | Detail |