Recombinant multi-species SCD5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SCD5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Stearoyl-CoA desaturase (SCD; EC 1.14.99.5) is an integral membrane protein of the endoplasmic reticulum that catalyzes the formation of monounsaturated fatty acids from saturated fatty acids. SCD may be a key regulator of energy metabolism with a role in obesity and dislipidemia. Four SCD isoforms, Scd1 through Scd4, have been identified in mouse. In contrast, only 2 SCD isoforms, SCD1 (MIM 604031) and SCD5, have been identified in human. SCD1 shares about 85% amino acid identity with all 4 mouse SCD isoforms, as well as with rat Scd1 and Scd2. In contrast, SCD5 shares limited homology with the rodent SCDs and appears to be unique to primates (Wang et al., 2005 [PubMed 15907797]).[supplied by OMIM, Mar 2008]
The Alternative Names of target: ACOD4,Acyl-CoA-desaturase 4,DFNA79,FADS4,HSCD5,SCD2,SCD4,SCD5,Stearoyl-CoA 9-desaturase,Stearoyl-CoA desaturase 2,Stearoyl-CoA desaturase 5
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1583-Ag-1/ GM-Tg-hg-IP1583-Ag-2 | Human SCD5 protein | Human |
| GM-Tg-rg-IP1583-Ag-1/ GM-Tg-rg-IP1583-Ag-2 | Rat SCD5 protein | Rat |
| GM-Tg-mg-IP1583-Ag-1/ GM-Tg-mg-IP1583-Ag-2 | Mouse SCD5 protein | Mouse |
| GM-Tg-cynog-IP1583-Ag-1/ GM-Tg-cynog-IP1583-Ag-2 | Cynomolgus/Rhesus macaque SCD5 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1583-Ag-1/ GM-Tg-felg-IP1583-Ag-2 | Feline SCD5 protein | Feline |
| GM-Tg-cang-IP1583-Ag-1/ GM-Tg-cang-IP1583-Ag-2 | Canine SCD5 protein | Canine |
| GM-Tg-bovg-IP1583-Ag-1/ GM-Tg-bovg-IP1583-Ag-2 | Bovine SCD5 protein | Bovine |
| GM-Tg-equg-IP1583-Ag-1/ GM-Tg-equg-IP1583-Ag-2 | Equine SCD5 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP1583-Ag-1/ GM-Tg-hg-IP1583-Ag-2;
GM-Tg-rg-IP1583-Ag-1/ GM-Tg-rg-IP1583-Ag-2;
GM-Tg-mg-IP1583-Ag-1/ GM-Tg-mg-IP1583-Ag-2; GM-Tg-cynog-IP1583-Ag-1/ GM-Tg-cynog-IP1583-Ag-2; GM-Tg-felg-IP1583-Ag-1/ GM-Tg-felg-IP1583-Ag-2; GM-Tg-cang-IP1583-Ag-1/ GM-Tg-cang-IP1583-Ag-2; GM-Tg-bovg-IP1583-Ag-1/ GM-Tg-bovg-IP1583-Ag-2; GM-Tg-equg-IP1583-Ag-1/ GM-Tg-equg-IP1583-Ag-2 |
| Products Name | SCD5 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | SCD5 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SCD5 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.