Explore SCD5 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
Stearoyl-CoA desaturase (SCD; EC 1.14.99.5) is an integral membrane protein of the endoplasmic reticulum that catalyzes the formation of monounsaturated fatty acids from saturated fatty acids. SCD may be a key regulator of energy metabolism with a role in obesity and dislipidemia. Four SCD isoforms, Scd1 through Scd4, have been identified in mouse. In contrast, only 2 SCD isoforms, SCD1 (MIM 604031) and SCD5, have been identified in human. SCD1 shares about 85% amino acid identity with all 4 mouse SCD isoforms, as well as with rat Scd1 and Scd2. In contrast, SCD5 shares limited homology with the rodent SCDs and appears to be unique to primates (Wang et al., 2005 [PubMed 15907797]).[supplied by OMIM, Mar 2008]
| Target ID |
GM-IP1583
|
| Target Name |
SCD5
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
79966
|
| Gene ID |
100060968 (Equus caballus), 101090611 (Felis catus), 487831 (Canis lupus familiaris), 617419 (Bos taurus)
694079 (Macaca mulatta), 79966 (Homo sapiens)
|
| Target Alternative Names |
ACOD4,Acyl-CoA-desaturase 4,DFNA79,FADS4,HSCD5,SCD2,SCD4,SCD5,Stearoyl-CoA 9-desaturase,Stearoyl-CoA desaturase 2,Stearoyl-CoA desaturase 5
|
| Uniprot Accession |
Q2KIA4,Q86SK9
|
| Protein Sub-location |
Introcelluar Protein
|
| Disease from KEGG |
Metabolic pathways, PPAR signaling pathway, Alcoholic liver disease
|
| Gene Ensembl |
ENSECAG00000014698, ENSCAFG00845019428, ENSBTAG00000022449, ENSMMUG00000052743, ENSG00000145284
|
SCD5 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo79966 | Pre-made Human SCD5/SCD2/SCD4 siRNA oligo Duplex | 79966 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo694079 | Pre-made Cynomolgus/Rhesus macaque SCD5 siRNA oligo Duplex | 694079 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101090611 | Pre-made Cat/Feline SCD5 siRNA oligo Duplex | 101090611 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo487831 | Pre-made Dog/Canine SCD5 siRNA oligo Duplex | 487831 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo617419 | Pre-made Bovines/Cattle SCD5 siRNA oligo Duplex | 617419 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100060968 | Pre-made Equine/Horse SCD5 siRNA oligo Duplex | 100060968 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
SCD5 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP1583-Ab | Human | Anti-Human SCD5 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP1583-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque SCD5 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP1583-Ab | Cat/Feline | Anti-Cat/Feline SCD5 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP1583-Ab | Dog/Canine | Anti-Dog/Canine SCD5 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP1583-Ab | Bovines/Cattle | Anti-Bovines/Cattle SCD5 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP1583-Ab | Equine/Horse | Anti-Equine/Horse SCD5 monoclonal antibody | mab | | Detail |
SCD5 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP1583-Ag | Human | Human SCD5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP1583-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque SCD5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP1583-Ag | Cat/Feline | Cat/Feline SCD5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP1583-Ag | Dog/Canine | Dog/Canine SCD5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP1583-Ag | Bovines/Cattle | Bovines/Cattle SCD5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP1583-Ag | Equine/Horse | Equine/Horse SCD5 recombinant protein | Mammalian cell | Detail |
