Recombinant multi-species Raptor/RPTOR protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Raptor/RPTOR protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
The Alternative Names of target: 4932417H02Rik,KOG1,Mip1,RGD1311784,RPTOR,Rap,Raptor,Regulatory-associated protein of mTOR,Rptor,mKIAA1303,p150 target of rapamycin (TOR)-scaffold protein

Target products collectionGo to Raptor/RPTOR products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP1556-Ag-1/ GM-Tg-hg-IP1556-Ag-2 Human Raptor/RPTOR protein Human
GM-Tg-rg-IP1556-Ag-1/ GM-Tg-rg-IP1556-Ag-2 Rat Raptor/RPTOR protein Rat
GM-Tg-mg-IP1556-Ag-1/ GM-Tg-mg-IP1556-Ag-2 Mouse Raptor/RPTOR protein Mouse
GM-Tg-cynog-IP1556-Ag-1/ GM-Tg-cynog-IP1556-Ag-2 Cynomolgus/Rhesus macaque Raptor/RPTOR protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP1556-Ag-1/ GM-Tg-felg-IP1556-Ag-2 Feline Raptor/RPTOR protein Feline
GM-Tg-cang-IP1556-Ag-1/ GM-Tg-cang-IP1556-Ag-2 Canine Raptor/RPTOR protein Canine
GM-Tg-bovg-IP1556-Ag-1/ GM-Tg-bovg-IP1556-Ag-2 Bovine Raptor/RPTOR protein Bovine
GM-Tg-equg-IP1556-Ag-1/ GM-Tg-equg-IP1556-Ag-2 Equine Raptor/RPTOR protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP1556-Ag-1/ GM-Tg-hg-IP1556-Ag-2; GM-Tg-rg-IP1556-Ag-1/ GM-Tg-rg-IP1556-Ag-2;
GM-Tg-mg-IP1556-Ag-1/ GM-Tg-mg-IP1556-Ag-2; GM-Tg-cynog-IP1556-Ag-1/ GM-Tg-cynog-IP1556-Ag-2;
GM-Tg-felg-IP1556-Ag-1/ GM-Tg-felg-IP1556-Ag-2; GM-Tg-cang-IP1556-Ag-1/ GM-Tg-cang-IP1556-Ag-2;
GM-Tg-bovg-IP1556-Ag-1/ GM-Tg-bovg-IP1556-Ag-2; GM-Tg-equg-IP1556-Ag-1/ GM-Tg-equg-IP1556-Ag-2
Products Name Raptor/RPTOR protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name Raptor/RPTOR
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Raptor/RPTOR protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.