Explore Raptor/RPTOR gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
| Target ID |
GM-IP1556
|
| Target Name |
Raptor/RPTOR
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
57521
|
| Gene ID |
100056244 (Equus caballus), 101086862 (Felis catus), 287871 (Rattus norvegicus), 507056 (Bos taurus) 57521 (Homo sapiens), 608378 (Canis lupus familiaris), 712848 (Macaca mulatta), 74370 (Mus musculus)
|
| Target Alternative Names |
4932417H02Rik,KOG1,Mip1,RGD1311784,RPTOR,Rap,Raptor,Regulatory-associated protein of mTOR,Rptor,mKIAA1303,p150 target of rapamycin (TOR)-scaffold protein
|
| Uniprot Accession |
Q8N122,Q8K4Q0
|
| Protein Sub-location |
Introcelluar Protein
|
| Disease from KEGG |
PI3K-Akt signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species
|
| Gene Ensembl |
ENSECAG00000017757, ENSBTAG00000002883, ENSG00000141564, ENSCAFG00845012286, ENSMMUG00000006761, ENSMUSG00000025583
|
Pre-made viral vector of Raptor/RPTOR cDNA Clones/ORF Plasmid
Raptor/RPTOR siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo57521 | Pre-made Human RPTOR/KOG1/Mip1 siRNA oligo Duplex | 57521 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo287871 | Pre-made Rat Rptor/RGD1311784 siRNA oligo Duplex | 287871 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo74370 | Pre-made Mouse Rptor/Rap/Raptor siRNA oligo Duplex | 74370 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo712848 | Pre-made Cynomolgus/Rhesus macaque RPTOR siRNA oligo Duplex | 712848 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101086862 | Pre-made Cat/Feline RPTOR siRNA oligo Duplex | 101086862 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo608378 | Pre-made Dog/Canine RPTOR siRNA oligo Duplex | 608378 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo507056 | Pre-made Bovines/Cattle RPTOR siRNA oligo Duplex | 507056 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100056244 | Pre-made Equine/Horse RPTOR siRNA oligo Duplex | 100056244 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Raptor/RPTOR antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP1556-Ab | Human | Anti-Human Raptor/RPTOR monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP1556-Ab | Rat | Anti-Rat Raptor/RPTOR monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP1556-Ab | Mouse | Anti-Mouse Raptor/RPTOR monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP1556-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Raptor/RPTOR monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP1556-Ab | Cat/Feline | Anti-Cat/Feline Raptor/RPTOR monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP1556-Ab | Dog/Canine | Anti-Dog/Canine Raptor/RPTOR monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP1556-Ab | Bovines/Cattle | Anti-Bovines/Cattle Raptor/RPTOR monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP1556-Ab | Equine/Horse | Anti-Equine/Horse Raptor/RPTOR monoclonal antibody | mab | | Detail |
Raptor/RPTOR recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP1556-Ag | Human | Human Raptor/RPTOR recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP1556-Ag | Rat | Rat Raptor/RPTOR recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP1556-Ag | Mouse | Mouse Raptor/RPTOR recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP1556-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Raptor/RPTOR recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP1556-Ag | Cat/Feline | Cat/Feline Raptor/RPTOR recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP1556-Ag | Dog/Canine | Dog/Canine Raptor/RPTOR recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP1556-Ag | Bovines/Cattle | Bovines/Cattle Raptor/RPTOR recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP1556-Ag | Equine/Horse | Equine/Horse Raptor/RPTOR recombinant protein | Mammalian cell | Detail |