Recombinant multi-species RUBCN protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RUBCN protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a negative regulator of autophagy and endocytic trafficking and controls endosome maturation. This protein contains two conserved domains, an N-terminal RUN domain and a C-terminal DUF4206 domain. The RUN domain is involved in Ras-like GTPase signaling, and the DUF4206 domain contains a diacylglycerol (DAG) binding-like motif. Mutation in this gene results in deletion of the DAG binding-like motif and causes a recessive ataxia. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
The Alternative Names of target: 1700021K19Rik,5330403K09,Beclin-1 associated RUN domain containing protein (Baron),KIAA0226,RGD1305422,RUBCN,RUBICON,Rubcn,Rubicon,Run domain Beclin-1-interacting and cysteine-rich domain-containing protein,SCAR15,mKIAA0226

Target products collectionGo to RUBCN products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP13880-Ag-1/ GM-Tg-hg-IP13880-Ag-2 Human RUBCN protein Human
GM-Tg-rg-IP13880-Ag-1/ GM-Tg-rg-IP13880-Ag-2 Rat RUBCN protein Rat
GM-Tg-mg-IP13880-Ag-1/ GM-Tg-mg-IP13880-Ag-2 Mouse RUBCN protein Mouse
GM-Tg-cynog-IP13880-Ag-1/ GM-Tg-cynog-IP13880-Ag-2 Cynomolgus/Rhesus macaque RUBCN protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP13880-Ag-1/ GM-Tg-felg-IP13880-Ag-2 Feline RUBCN protein Feline
GM-Tg-cang-IP13880-Ag-1/ GM-Tg-cang-IP13880-Ag-2 Canine RUBCN protein Canine
GM-Tg-bovg-IP13880-Ag-1/ GM-Tg-bovg-IP13880-Ag-2 Bovine RUBCN protein Bovine
GM-Tg-equg-IP13880-Ag-1/ GM-Tg-equg-IP13880-Ag-2 Equine RUBCN protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP13880-Ag-1/ GM-Tg-hg-IP13880-Ag-2; GM-Tg-rg-IP13880-Ag-1/ GM-Tg-rg-IP13880-Ag-2;
GM-Tg-mg-IP13880-Ag-1/ GM-Tg-mg-IP13880-Ag-2; GM-Tg-cynog-IP13880-Ag-1/ GM-Tg-cynog-IP13880-Ag-2;
GM-Tg-felg-IP13880-Ag-1/ GM-Tg-felg-IP13880-Ag-2; GM-Tg-cang-IP13880-Ag-1/ GM-Tg-cang-IP13880-Ag-2;
GM-Tg-bovg-IP13880-Ag-1/ GM-Tg-bovg-IP13880-Ag-2; GM-Tg-equg-IP13880-Ag-1/ GM-Tg-equg-IP13880-Ag-2
Products Name RUBCN protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name RUBCN
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RUBCN protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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